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University of Technology Sydney home University of Technology Sydney home
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  2. arrow_forward_ios ... About UTS
  3. arrow_forward_ios ... Information on Faculties...
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  5. arrow_forward_ios ... School of Life Sciences
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  7. arrow_forward_ios Healthy Futures
  8. arrow_forward_ios Pregnancy and cardiovascular disease

Pregnancy and cardiovascular disease

explore
  • Our research
    • Healthy Futures
      • arrow_forward Advanced tissue engineering and stem cell biology
      • arrow_forward Cancer Biology Group
      • arrow_forward Chlamydia in Women and Australian Wildlife
      • arrow_forward Forensic Predictive Imaging Unit
      • arrow_forward Gene therapy and translational molecular analysis laboratory
      • arrow_forward Helminth Immunology
      • arrow_forward The Labbate Group
      • arrow_forward Laboratory of Cellular and Molecular Neuroscience
      • arrow_forward Neural Injury Research Unit
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      • arrow_forward Parasite transmission immunity and vaccine
      • arrow_forward Pregnancy and cardiovascular disease
      • arrow_forward Programming and development
      • arrow_forward Respiratory Research Group
      • arrow_forward Simpson Laboratory
      • arrow_forward Translational Airways Group
      • arrow_forward Translational Oncology Group
      • arrow_forward UTS Centenary Centre for Inflammation
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    • arrow_forward Impact of our research
    • Life Sciences Technologies
      • arrow_forward Hack the Cell
      • arrow_forward Membrane Biophysics Group

Focus

Women's health

 

Group leader

Dr Lana McClements

The research in our group focuses on discovery of novel pathogenic mechanisms in cardiovascular disease in pregnancy i.e. pre-eclampsia, and beyond, in the presence or absence of diabetes.

These novel molecular mechanisms involve proteins or miRNAs which can be explored as early disease biomarkers, or targets for novel therapies such as mesenchymal stem cells.

The translational aspects of our research include:

  • the development of a novel anti-angiogenic agent (AD-01/AML201) for the treatment of solid cancer
  • a patented technology for early prediction of pre-eclampsia (WO2018051125A1) and
  • a digital technology for home monitoring of high-risk pregnancies.

In collaboration with Prof. Dayong Jin we have been developing a novel point of care pre-eclampsia test which will allow early detection of this disease in pregnancy and potentially reduce complications to both mothers and their offspring. This research is based on three pillars of investigations including in vitro models, in vivo models and patient samples. 

Acknowledgement of Country

UTS acknowledges the Gadigal People of the Eora Nation and the Boorooberongal People of the Dharug Nation upon whose ancestral lands our campuses now stand. We would also like to pay respect to the Elders both past and present, acknowledging them as the traditional custodians of knowledge for these lands. 

University of Technology Sydney

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15 Broadway, Ultimo, NSW 2007

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