A/Prof Sally Inglis is a NSW Cardiovascular Research Network Life Science Fellow, supported by the Heart Foundation and the NSW Office for Medical Research (2013-2017). Her research interests are chronic cardiovascular diseases, including peripheral arterial disease and heart failure. During her NHMRC and Heart Foundation Sidney Sax Fellowship (2008-2013), she spent 2 years at the University of Glasgow establishing a new program of research into the epidemiology, natural history and management of peripheral arterial disease using the Scottish Morbidity Record and the Scottish Health Survey. Since joining UTS in 2011, Sally has established a program of research into the management of peripheral arterial disease in Australia and the use of health technology to support people with heart failure. Sally has completed a large Cochrane review of telemonitoring in heart failure and is also leading Cochrane reviews examining self-management interventions for people with peripheral arterial disease and the use of m-health technology for health education in heart failure.
Nurse Fellow of the European Society of Cardiology
Affiliate member, Cardiac Society of Australia and New Zealand
Member, Australasian College of Cardiovascular Nursing
Member, Heart Failure Society of the European Society of Cardiology
Member, Council on Cardiovascular Nursing and Allied Health Professionals of the European Society of Cardiology
Committee Member, Australasian College of Cardiovascular Nursing
Can supervise: YES
Peripheral arterial disease
Chronic heart failure
Post-discharge management of chronic cardiovascular disease
Nursing – undergraduate/post-graduate research methods
Stewart, S, Inglis, S & Hawkes, A 2006, A Practical Guide to Specialist Nurse Management., Blackwell Publishing, BMJ Books, Massachusetts.
Arnold, RH, Tideman, PA, Devlin, GP, Carroll, GE, Elder, A, Lowe, H, Macdonald, PS, Bannon, PG, Juergens, C, McGuire, M, Mariani, JA, Coffey, S, Faddy, S, Brown, A, Inglis, S & Wang, WYS 2020, 'Rural and Remote Cardiology During the COVID-19 Pandemic: Cardiac Society of Australia and New Zealand (CSANZ) Consensus Statement.', Heart, lung & circulation, vol. 29, no. 7, pp. e88-e93.View/Download from: Publisher's site
THE CHALLENGES:Rural and remote Australians and New Zealanders have a higher rate of adverse outcomes due to acute myocardial infarction, driven by many factors. The prevalence of cardiovascular disease (CVD) is also higher in regional and remote populations, and people with known CVD have increased morbidity and mortality from coronavirus disease 2019 (COVID-19). In addition, COVID-19 is associated with serious cardiac manifestations, potentially placing additional demand on limited regional services at a time of diminished visiting metropolitan support with restricted travel. Inter-hospital transfer is currently challenging as receiving centres enact pandemic protocols, creating potential delays, and cardiovascular resources are diverted to increasing intensive care unit (ICU) and emergency department (ED) capacity. Regional and rural centres have limited staff resources, placing cardiac services at risk in the event of staff infection or quarantine during the pandemic. MAIN RECOMMENDATIONS:Health districts, cardiologists and government agencies need to minimise impacts on the already vulnerable cardiovascular health of regional and remote Australians and New Zealanders throughout the COVID-19 pandemic. Changes in management should include.
Disler, RT, Spiliopoulos, N, Inglis, SC, Currow, DC & Davidson, PM 2020, 'Cognitive screening in chronic obstructive pulmonary disease: patient's perspectives.', Disability and rehabilitation, vol. 42, no. 9, pp. 1233-1239.View/Download from: Publisher's site
Purpose: Cognitive impairment is highly prevalent (61%) in chronic obstructive pulmonary disease (COPD). International guidelines recommend providing self-management education through resource-intensive, pulmonary rehabilitation programs, yet screening for deficits likely to interfere with learning have received insufficient attention. Concerns over cognitive testing as confronting are described by health professionals as a barrier to screening, but with minimal empiric data. This study explored views on cognitive impairment and screening in patients with COPD.Design: Qualitative study, focus groups.Methods: Participants with COPD were recruited from a respiratory service at a regional hospital. Conversations were recorded, transcribed verbatim, and analyzed using thematic analysis.Results: Focus groups were undertaken between February and May 2014. Fifteen patients, with a diagnosis of COPD and mean age of 73, participated. Thematic analysis resulted in four overall themes: (1) limited awareness of the connection between cognitive change and COPD; (2) cognitive change as part of normal ageing; (3) current strategies for self-management activities and cognition functioning; and (4) attitudes to cognitive testing.Conclusions: This study identified that participants were open to discussing issues of cognitive function suggesting that normalizing discussion around cognitive change presents an opportunity to introduce screening within routine assessments. Identifying cognitive impairment provides opportunity to tailor rehabilitation for those at risk of sub-optimal self-management.Implications for RehabilitationChanges in cognition are recognized as a barrier to optimal self-management and rehabilitation efficacy in chronic disease.This study identified that participants were open to discussing issues of cognitive function suggesting that normalizing discussion around cognitive change presents an opportunity to introduce screening within routine assessments.Identifyi...
Allida, S, Du, H, Xu, X, Prichard, R, Chang, S, Hickman, LD, Davidson, PM & Inglis, SC 2020, 'mHealth education interventions in heart failure.', The Cochrane database of systematic reviews, no. 7.View/Download from: Publisher's site
BACKGROUND:Heart failure (HF) is a chronic disease with significant impact on quality of life and presents many challenges to those diagnosed with the condition, due to a seemingly complex daily regimen of self-care which includes medications, monitoring of weight and symptoms, identification of signs of deterioration and follow-up and interaction with multiple healthcare services. Education is vital for understanding the importance of this regimen, and adhering to it. Traditionally, education has been provided to people with heart failure in a face-to-face manner, either in a community or a hospital setting, using paper-based materials or video/DVD presentations. In an age of rapidly-evolving technology and uptake of smartphones and tablet devices, mHealth-based technology (defined by the World Health Organization as mobile and wireless technologies to achieve health objectives) is an innovative way to provide health education which has the benefit of being able to reach people who are unable or unwilling to access traditional heart failure education programmes and services. OBJECTIVES:To systematically review and quantify the potential benefits and harms of mHealth-delivered education for people with heart failure. SEARCH METHODS:We performed an extensive search of bibliographic databases and registries (CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO, IEEE Xplore, ClinicalTrials.gov and WHO International Clinical Trials Registry Platform (ICTRP) Search Portal), using terms to identify HF, education and mHealth. We searched all databases from their inception to October 2019 and imposed no restriction on language of publication. SELECTION CRITERIA:We included studies if they were conducted as a randomised controlled trial (RCT), involving adults (≥ 18 years) with a diagnosis of HF. We included trials comparing mHealth-delivered education such as internet and web-based education programmes for use on smartphones and tablets (including apps) and other mobile devices, S...
Xu, X, Ling, M, Inglis, SC, Hickman, L & Parker, D 2020, 'Eating and healthy ageing: a longitudinal study on the association between food consumption, memory loss and its comorbidities.', International journal of public health, vol. 65, no. 5, pp. 571-582.View/Download from: Publisher's site
OBJECTIVES:To explore the longitudinal association between food groups and memory loss and comorbid heart disease and diabetes (both Type 1 and 2) for people living in New South Wales, Australia. METHODS:We assessed 139,096 adults (aged 45 years and over) from the 45 and Up Study who completed both baseline (2006-2009) and follow-up (2012-2015) surveys. Mixed linear and generalized estimating equation models were used to examine the longitudinal associations. RESULTS:High consumption of fruit, vegetable and protein-rich food associated with lower odds of memory loss. High consumption of fruit and vegetables also associated with lower odds of comorbid heart disease (p ≤ 0.001). People who aged ≥ 80 years with low consumption of cereals had the highest odds of memory loss and comorbid heart disease than people in other age groups (p < 0.01). CONCLUSIONS:The results highlighted the longitudinal association of fruit and vegetable in relation to memory loss and comorbid heart disease. Age effects on cereals consumption which have an influence on memory loss and comorbid heart disease.
Ferguson, C, Inglis, SC, Breen, PP, Gargiulo, GD, Byiers, V, Macdonald, PS & Hickman, LD 2020, 'Clinician Perspectives on the Design and Application of Wearable Cardiac Technologies for Older Adults: Qualitative Study.', Jmir Aging, vol. 3, no. 1.View/Download from: Publisher's site
BACKGROUND: New wearable devices (for example, AliveCor or Zio patch) offer promise in detecting arrhythmia and monitoring cardiac health status, among other clinically useful parameters in older adults. However, the clinical utility and usability from the perspectives of clinicians is largely unexplored. OBJECTIVE: This study aimed to explore clinician perspectives on the use of wearable cardiac monitoring technology for older adults. METHODS: A descriptive qualitative study was conducted using semistructured focus group interviews. Clinicians were recruited through purposive sampling of physicians, nurses, and allied health staff working in 3 tertiary-level hospitals. Verbatim transcripts were analyzed using thematic content analysis to identify themes. RESULTS: Clinicians representing physicians, nurses, and allied health staff working in 3 tertiary-level hospitals completed 4 focus group interviews between May 2019 and July 2019. There were 50 participants (28 men and 22 women), including cardiologists, geriatricians, nurses, and allied health staff. The focus groups generated the following 3 overarching, interrelated themes: (1) the current state of play, understanding the perceived challenges of patient cardiac monitoring in hospitals, (2) priorities in cardiac monitoring, what parameters new technologies should measure, and (3) cardiac monitoring of the future, "the ideal device." CONCLUSIONS: There remain pitfalls related to the design of wearable cardiac technology for older adults that present clinical challenges. These pitfalls and challenges likely negatively impact the uptake of wearable cardiac monitoring in routine clinical care. Partnering with clinicians and patients in the co-design of new wearable cardiac monitoring technologies is critical to optimize the use of these devices and their uptake in clinical care.
Hickman, L, Ferguson, C, Davidson, PM, Allida, S, Inglis, S, Parker, D & Agar, M 2020, 'Key elements of interventions for heart failure patients with mild cognitive impairment or dementia: A systematic review.', European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology, vol. 19, no. 1, pp. 8-19.View/Download from: Publisher's site
BACKGROUND:The purpose of this systematic review was to (a) examine the effects of interventions delivered by a heart failure professional for mild cognitive impairment and dementia on cognitive function, memory, working memory, instrumental activities of daily living, heart failure knowledge, self-care, quality of life and depression; and (b) identify the successful elements of these strategies for heart failure patients with mild cognitive impairment or dementia. METHODS AND RESULTS:During March 2018, an electronic search of databases including CINAHL, MEDLINE, EMBASE and PsycINFO was conducted. All randomised controlled trials, which examined an intervention strategy to help heart failure patients with mild cognitive impairment or dementia cope with self-care, were included. An initial search yielded 1622 citations, six studies were included (N= 595 participants, mean age 68 years). There were no significant improvements in cognitive function and depression. However, significant improvements were seen in memory (p=0.015), working memory (p=0.029) and instrumental activities of daily living (p=0.006). Nurse led interventions improved the patient's heart failure knowledge (p=0.001), self-care (p<0.05) and quality of life (p=0.029). Key elements of these interventions include brain exercises, for example, syllable stacks, individualised assessment and customised education, personalised self-care schedule development, interactive problem-solving training on scenarios and association techniques to prompt self-care activities. CONCLUSIONS:Modest evidence for nurse led interventions among heart failure patients with mild cognitive impairment or dementia was identified. These results must be interpreted with caution in light of the limited number of available included studies.
Disler, RT, Inglis, SC, Newton, P, Currow, DC, Macdonald, PS, Glanville, AR, Donesky, D, Carrieri-Kohlman, V & Davidson, PM 2019, 'Older Patients' Perspectives of Online Health Approaches in Chronic Obstructive Pulmonary Disease.', Telemedicine Journal and e-Health, vol. 25, no. 9.View/Download from: Publisher's site
BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a complex, chronic condition. Patients commonly have limited access to face-to-face support due to decreased mobility, symptom burden, and availability of services. Online health care approaches provide the potential for increased access to self-management education and support. This study sought to understand older patients with COPD's perspectives of online approaches to health care. MATERIALS AND METHODS:Participants older than 65 years were recruited from a respiratory service at an academic medical center. Qualitative, focus groups were used and recorded, transcribed verbatim, and analyzed using thematic analysis to identify key and repeated emergent themes. RESULTS:Focus groups were undertaken between January and May 2014. Thematic analysis resulted in five overall themes: (1) concern over risks in the online environment; (2) multimedia and technology use as part of everyday life; (3) online resources as an opportunity for revision of forgotten knowledge; (5) potential for facilitation of decision-making support across geographical and physical barriers; and (4) perceived benefits of online peer support for people with COPD. CONCLUSIONS:Overall, these older participants with COPD had positive views of online health information, but did raise the need for guidance to ensure valid and reliable online sources. The capacity for online sources to increase access to decision support and up-to-date information was viewed positively, as was the ability to interact with peers who had similar experiences. Telecommunication tools and approaches are already being utilized in health care interactions. Further research is required into the most appropriate, feasible, and sustainable online health approaches to support patients with chronic illnesses such as COPD.
Atsalos, C, Payk, M, O'Neill, A, Inglis, S, Cheung, NW & Jackson, D 2019, 'Meeting the challenges posed by an escalating diabetes healthcare burden: A mixed methods study.', Contemporary Nurse, pp. 1-17.View/Download from: Publisher's site
Background: The ongoing escalation in the incidence of diabetes is contributing to a growing burden on health services because patients with diabetes as a co-morbidity are now spread throughout the hospital (rather than being located in specific areas). Thus, there is a need for expertise in diabetes care throughout services to ensure optimal care and reduce threats to patient safety. Aims and objectives: To identify new strategies to maintain optimal care for patients with diabetes while in hospital. Design: Mixed methods underpinned by Appreciative Inquiry. Methods: The Diabetes Knowledge Questionnaire Survey (DKQS) (n = 173); focus group interviews with nurses and midwives (n = 40), and individual interviews with recently discharged hospital patients (n = 6). Quantitative data were analysed using descriptive statistics and qualitative data by thematic analysis. Results: Highlight a need to enhance knowledge and confidence of diabetes management among nursing, midwifery, medical and ancillary staff through the introduction of focused education strategies. This, together with improved communication and team work, is required to relieve the burdens on frontline nursing staff and patients caused by delays in prescribing and reviewing insulin requirements and in accessing needed food for people with diabetes. Conclusions: In seeking solutions to the challenges in caring for hospitalised patients with diabetes there is a need to work across the entire hospital workforce and to develop effective and efficient methods for ensuring appropriate skills and knowledge of diabetes management for staff across complex and rapidly changing hospital systems. Relevance to clinical practice: The introduction and implementation of innovative educational and organisational strategies are needed to assist in meeting the challenges posed by an escalating diabetes healthcare burden. The safety of patients with diabetes can be optimised with the timely availability of appropriate meals...
Kang, K, Gholizadeh, L, Inglis, SC & Han, H-R 2019, 'Validation of the Korean Version of the MacNew Heart Disease Health-Related Quality of Life Questionnaire.', The journal of nursing research : JNR, vol. 27, no. 2, pp. 1-7.View/Download from: Publisher's site
Health-related quality of life (HRQoL) is an importantconcept in patients with cardiac diseases, including myocardial infarction (MI). Disease-specific tools offer valuable insights into the impact of a disease on various aspects of a patient's life.The aim of this study was to assess the psychometric properties of the Korean version of the MacNew Heart Disease HRQoL Questionnaire (Korean MacNew).One hundred thirty-six patients who had experienced MI about 3 months earlier were recruited from two tertiary hospitalsin South Korea. The internal consistency and various types of validity of the Korean MacNew were assessed. Exploratory factor analysis with varimax rotation was performed to identify a better structure for this instrument.The internal consistency of the Korean MacNew was established with Cronbach's alpha coefficients ranging from .88 to .93. Face validity and construct validity (both discriminant and concurrent) of the Korean MacNew were established. Strong positive correlations were found between the total Korean MacNew and the single-item global QoL scale (r = .73, p < .001). As expected, the total Korean MacNew also had strong negative correlations with the Depression Anxiety and Stress Scale 21 (r = -.81, p < .001) and the single-item fatigue scale (r = -.51, p < .001). The outcomes of exploratory factor analysis showed a better result with the five-factor structure in the Korean MacNew.The Korean MacNew showed consistently acceptable psychometric properties of reliability and validity in patients with MI. Therefore, this instrument may be recommended for assessing the HRQoL of patients with MI in Korea. However, caution should be taken in using the subscale scores.
Xu, X, Parker, D, Inglis, SC & Byles, J 2019, 'Can regular long-term breakfast cereals consumption benefits lower cardiovascular diseases and diabetes risk? A longitudinal population-based study.', Annals of Epidemiology, vol. 37, pp. 43-50.e3.View/Download from: Publisher's site
PURPOSE:Studies indicate breakfast cereals may reduce the risk of overweight, cardiovascular diseases, and diabetes, but a limited number of longitudinal studies have explored these relationships, indicating the need for further assessment. METHODS:We used 45 and Up Study data to examine the longitudinal association between breakfast cereals (and different categories of cereals) and heart disease, stroke, and diabetes. Dietary consumption was assessed by a short food frequency questionnaire. Diagnosed heart disease, stroke, and diabetes were self-reported. Generalized estimating equation models were used to examine the longitudinal associations. RESULTS:Of a total of 142,503 participants (aged 45 years and older), people in the older age group (aged 80 or older) had significantly higher breakfast cereal consumption (P < .001) than those in the younger age group (aged 45-64 years). A significantly inverse association was found between breakfast muesli and heart disease, stroke, and diabetes across all age groups. Associations between other categories of breakfast cereals (biscuit, bran, and oat cereals) and these three diseases differed by age groups. A positive association was found between oat cereals and diabetes for people in the younger age groups (aged 80 years and younger), but not for people in the older age group (aged 80 years and older). CONCLUSIONS:The benefit of breakfast muesli consumption was highlighted in prevention of these three diseases. The result suggests that age-specific dietary guidelines, with a particular focus on the types of breakfast cereals consumption in prevention of chronic diseases for older people need to be developed.
Ferguson, C, Hickman, LD, Phillips, J, Newton, PJ, Inglis, SC, Lam, L & Bajorek, BV 2019, 'An mHealth intervention to improve nurses' atrial fibrillation and anticoagulation knowledge and practice: the EVICOAG study.', European Journal of Cardiovascular Nursing, vol. 18, no. 1, pp. 7-15.View/Download from: Publisher's site
There is a need to improve cardiovascular nurses' knowledge and practices related to stroke prevention, atrial fibrillation and anticoagulation therapy.The aim of this study was to evaluate the efficacy of EVICOAG - a novel mHealth, smartphone-based, spaced-learning intervention on nurses' knowledge of atrial fibrillation and anticoagulation.Nurses employed in four clinical specialties (neuroscience, stroke, rehabilitation, cardiology) across three hospitals were invited to participate. In this quasi-experimental study, 12 case-based atrial fibrillation and anticoagulation learning scenarios (hosted by an mHealth platform) were delivered to participants' smartphones over a 6-week period (July-December 2016) using a spaced timing algorithm. Electronic surveys to assess awareness and knowledge were administered pre (T1) and post (T2) intervention.From 74 participants recruited to T1, 40 completed T2. There was a 54% mean improvement in knowledge levels post-intervention. The largest improvement was achieved in domains related to medication interaction and stroke and bleeding risk assessment. Post-intervention, those who completed T2 were significantly more likely to use CHA2DS2-VASc (2.5% vs. 37.5%) and HAS-BLED (2.5% vs. 35%) tools to assess stroke and bleeding risk, respectively ( P<0.01).The EVICOAG intervention improved nurses' knowledge of atrial fibrillation and anticoagulation, and influenced their uptake and use of stroke and bleeding risk assessment tools in clinical practice. Future research should focus on whether a similar intervention might improve patient-centred outcomes such as patients' knowledge of their condition and therapies, medication adherence, time in the therapeutic range and quality of life.
Koo, K, Ferguson, C, Ling, LH, Cleland, JGF & Inglis, SC 2019, 'Implantable device monitoring versus usual care for managing individuals with heart failure', Cochrane Database of Systematic Reviews, vol. 2019, no. 8.View/Download from: Publisher's site
© 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of using implantable device monitoring as an additional management tool for individuals with heart failure, compared with usual care alone.
Koo, K, Inglis, SC, Freedman, B, Thijs, V & Ferguson, C 2019, 'Implantable cardiac monitors compared with conventional methods for the detection of atrial high-rate episodes in individuals with embolic stroke of undetermined source', Cochrane Database of Systematic Reviews, vol. 2019, no. 11.View/Download from: Publisher's site
Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:. To compare the benefits, harm and the atrial high-rate episode (AHRE) detection rate of implantable cardiac monitors against conventional methods (such as electrocardiogram, ambulatory Holter monitors, event monitors and real-time telemetry) in participants with embolic stroke of unknown source.
Kang, K, Gholizadeh, L, Han, H-R & Inglis, SC 2018, 'Predictors of health-related quality of life in korean patients with myocardial infarction: a longitudinal observational study.', Heart & lung : the journal of critical care, vol. 47, no. 2018, pp. 142-148.View/Download from: Publisher's site
Experience of myocardial infarction (MI) negatively affects different aspects of health-related quality of life (HRQoL).This study aimed to examine trends in HRQoL of MI patients and to identify demographic, clinical and psychosocial predictors of HRQoL at three months.A total of 150 patients in South Korea were completed the study questionnaires at baseline. After three months from discharge, 136 participants completed follow-up questionnaires, including the Korean version of the MacNew Quality of Life after Myocardial Infarction Questionnaire (MacNew).HRQoL significantly improved over three months. Younger age, ST-elevation MI, and higher LVEF, lower level of depression, better understanding of the illness and higher perceived social support at baseline were associated with better HRQoL at three months.Providing adequate information about the illness and social support as well as reducing negative psychological experiences in early days after MI may improve HRQoL of MI patients.
Dierckx, R, Inglis, SC, Clark, RA, Prieto-Merino, D & Cleland, JGF 2017, 'Telemedicine in heart failure: new insights from the Cochrane meta-analyses', EUROPEAN JOURNAL OF HEART FAILURE, vol. 19, no. 3, pp. 304-306.View/Download from: Publisher's site
Inglis, SC, Clark, RA, Dierckx, R, Prieto-Merino, D & Cleland, JGF 2017, 'Structured telephone support or non-invasive telemonitoring for patients with heart failure', Heart, vol. 103, no. 4, pp. 255-257.View/Download from: Publisher's site
Heart failure is a common and growing
problem, worldwide, often leading to
repeated hospitalisations, reduced quality
of life, disability, loss of independence
and shortened life expectancy. Managing
heart failure is costly and complex for
individual patients, their families and
healthcare systems. A range of pharmacological
agents, devices and disease management
programmes have proven to be
effective but are not available to all
patients. Non-invasive telemonitoring and
structured telephone support for patients
with heart failure have been researched
for almost two decades; however the jury
still appears to be out for the use of this
intervention in clinical practice
Franco-Trigo, L, Hossain, LN, Durks, D, Fam, D, Inglis, SC, Benrimoj, SI & Sabater-Hernández, D 2017, 'Stakeholder analysis for the development of a community pharmacy service aimed at preventing cardiovascular disease', Research in Social and Administrative Pharmacy, vol. 13, no. 3, pp. 539-552.View/Download from: Publisher's site
Participatory approaches involving stakeholders across the health care system can help enhance the development, implementation and evaluation of health services. These approaches may be particularly useful in planning community pharmacy services and so overcome challenges in their implementation into practice. Conducting a stakeholder analysis is a key first step since it allows relevant stakeholders to be identified, as well as providing planners a better understanding of the complexity of the health care system.The main aim of this study was to conduct a stakeholder analysis to identify those individuals and organizations that could be part of a leading planning group for the development of a community pharmacy service (CPS) to prevent cardiovascular disease (CVD) in Australia.An experienced facilitator conducted a workshop with 8 key informants of the Australian health care system. Two structured activities were undertaken. The first explored current needs and gaps in cardiovascular care and the role of community pharmacists. The second was a stakeholder analysis, using both ex-ante and ad-hoc approaches. Identified stakeholders were then classified into three groups according to their relative influence on the development of the pharmacy service. The information gathered was analyzed using qualitative content analysis.The key informants identified 46 stakeholders, including (1) patient/consumers and their representative organizations, (2) health care providers and their professional organizations and (3) institutions and organizations that do not directly interact with patients but organize and manage the health care system, develop and implement health policies, pay for health care, influence funding for health service research or promote new health initiatives. From the 46 stakeholders, a core group of 12 stakeholders was defined. These were considered crucial to the service's development because they held positions that could drive or inhibit progress. Sec...
Deek, H, Chang, S, Newton, PJ, Noureddine, S, Inglis, SC, Arab, GA, Kabbani, S, Chalak, W, Timani, N, Macdonald, PS & Davidson, PM 2017, 'An evaluation of involving family caregivers in the self-care of heart failure patients on hospital readmission: Randomised controlled trial (the FAMILY study).', International Journal of Nursing Studies, vol. 75, pp. 101-111.View/Download from: Publisher's site
BACKGROUND: The prevalence of heart failure is increasing in Lebanon but to date there is no systematic evaluation of a disease management intervention. OBJECTIVE: The aim of this study was to evaluate the effect of involving family caregivers in the self-care of patients with heart failure on the risk of hospital readmission. DESIGN: A multi-site, block randomised controlled trial. SETTINGS: The study was conducted over a 13-month period in three tertiary medical centres in Beirut and Mount Lebanon, Lebanon. PARTICIPANTS: Adult patients presenting for an exacerbation of heart failure to one of the study centres were included. Patients with limited life expectancy or physical functionality, planned cardiac bypass or valve replacement surgery, living alone or in nursing homes, or aged less than 18 years were excluded. METHODS: Patients allocated to the intervention group and their family caregivers were provided with a comprehensive, culturally appropriate, educational session on self-care maintenance and symptom management along with self-care resources. The usual care group received the self-care resources only. Follow-up phone calls were conducted 30days following discharge by a research assistant blinded to treatment assignment. The primary outcome was hospital readmission and the secondary outcomes were self-care, quality of life, major vascular events and healthcare utilization. RESULTS: The final sample included 256 patients hospitalized for heart failure randomised into control (130 patients) and intervention (126 patients) groups. The mean age was 67 (SD=8)years, and the majority (55%) were male. Readmission at 30days was significantly lower in the intervention group compared to the control group (n=10, 9% vs. n=20, 19% respectively, OR=0.40, 95% CI=0.02, 0.10, p=0.02). Self-care scores improved in both groups at 30days, with a significantly larger improvement in the intervention group than the control group in the maintenance and confidence sub-scales, b...
Kang, K, Gholizadeh, L, Inglis, SC & Han, H-R 2017, 'Correlates of health-related quality of life in patients with myocardial infarction: A literature review.', International Journal of Nursing Studies, vol. 73, pp. 1-16.View/Download from: Publisher's site
BACKGROUND: By the increasing emphasis on health-related quality of life (HRQoL) in patients with myocardial infarction (MI), it is necessary to explore factors that affect HRQoL in this population. OBJECTIVES: This study aimed to identify correlates of HRQoL in patients with MI. DESIGN: A literature review of the factors that affect HRQoL in patients with MI (1995-2016). DATA SOURCES: Three main databases-CINAHL, MEDLINE and PsychINFO-were searched to retrieve relevant peer-reviewed articles published in English. REVIEW METHODS: In consultation with a medical librarian, we identified relevant MeSH terms and used them for searching the literature: health-related quality of life/quality of life/HRQoL/QoL, myocardial infarction/heart attack/MI and predict*/factor. Data elements were extracted and narratively described variables synthesised into four categories. RESULTS: A total of 48 studies met the inclusion criteria and were included in the review. Correlates of HRQoL in patients with MI were identified in the following categories: demographic, behavioural, disease-related, and psychosocial factors. Specific correlates included age and gender-identity for demographic factors; physical activity and smoking for behavioural factors; severity of MI, symptoms, and comorbidities for disease-related factors; anxiety and depression for psychosocial factors. CONCLUSIONS: Identifying correlates of HRQoL can help identify patients who are at risk for poor HRQoL in the recovery or rehabilitation stage of post-MI. Future intervention should focus on adjustable correlates such as behavioural and psychosocial factors to promote HRQoL among patients after experiencing MI.
Ferguson, C, Inglis, SC, Newton, PJ, Middleton, S, Macdonald, PS & Davidson, PM 2017, 'Barriers and enablers to adherence to anticoagulation in heart failure with atrial fibrillation: patient and provider perspectives', Journal of Clinical Nursing, vol. 26, no. 23-24, pp. 4325-4334.View/Download from: Publisher's site
Aims & Objectives
The purpose of this study was to elucidate the barriers and enablers to adherence to anticoagulation in individuals with chronic heart failure (CHF) with concomitant atrial fibrillation (AF) from the perspective of patients and providers.
CHF and AF commonly coexist and are associated with increased stroke risk and mortality. Oral anticoagulation significantly reduces stroke risk and improves outcomes. Yet, in approximately 30% of cases anticoagulation is not commenced for a variety of reasons.
Qualitative study using narrative inquiry.
Data from face to face individual interviews with patients and information retrieved from healthcare file note review documented the clinician perspective. This study is a synthesis of the two data sources, obtained during patient clinical assessments as part of the Atrial Fibrillation And Stroke Thromboprophylaxis in hEart failuRe (AFASTER) Study.
Patient choice and preference were important factors in anticoagulation decisions, including treatment burden, unfavourable or intolerable side effects and patient refusal. Financial barriers included cost of travel, medication cost and reimbursement. Psychological factors included psychiatric illness, cognitive impairment and depression. Social barriers included homelessness and the absence of a caregiver or lack of caregiver assistance. Clinician reticence included fear of falls, frailty, age, fear of bleeding and the challenges of multi-morbidity. Facilitators to successful prescription and adherence were caregiver support, reminders and routine, self-testing and the use of technology.
Many barriers remain to high risk individuals being prescribed anticoagulation for stroke prevention. There are a number of enabling factors that facilitate prescription and optimize treatment adherence. Nurses should challenge these treatment barriers and seek enabling factors to optimise therapy.
Relevance to clinical practice
Ferguson, C, Inglis, SC, Newton, PJ, Middleton, S, Macdonald, PS & Davidson, PM 2017, 'Multi-morbidity, frailty and self-care: important considerations in treatment with anticoagulation drugs. Outcomes of the AFASTER study.', European Journal of Cardiovascular Nursing, vol. 16, no. 2, pp. 113-124.View/Download from: Publisher's site
Chronic heart failure (CHF) and atrial fibrillation (AF) are complex cardiogeriatric syndromes mediated by physical, psychological and social factors. Thromboprophylaxis is an important part of avoiding adverse events in these syndromes, particularly stroke.This study sought to describe the clinical characteristics of a cohort of patients admitted to hospital with CHF and concomitant AF and to document the rate and type of thromboprophylaxis. We examined the practice patterns of the prescription of treatment and determined the predictors of adverse events.Prospective consecutive participants with CHF and concomitant AF were enrolled during the period April to October 2013. Outcomes were assessed at 12 months, including all-cause readmission to hospital and mortality, stroke or transient ischaemic attack, and bleeding.All-cause readmission to hospital was frequent (68%) and the 12-month all-cause mortality was high (29%). The prescription of anticoagulant drugs at discharge was statistically significantly associated with a lower mortality at 12 months (23 vs. 40%; p=0.037; hazards ratio 0.506; 95% confidence interval 0.267-0.956), but was not associated with lower rates of readmission to hospital among patients with CHF and AF. Sixty-six per cent of participants were prescribed anticoagulant drugs on discharge from hospital. Self-reported self-care behaviour and 'not for cardiopulmonary resuscitation' were associated with not receiving anticoagulant drugs at discharge. Although statistical significance was not achieved, those patients who were assessed as frail or having greater comorbidity were less likely to receive anticoagulant drugs at discharge.This study highlights multi-morbidity, frailty and self-care to be important considerations in thromboprophylaxis. Shared decision-making with patients and caregivers offers the potential to improve treatment knowledge, adherence and outcomes in this group of patients with complex care needs.
Deek, H, Noureddine, S, Newton, PJ, Inglis, SC, MacDonald, PS & Davidson, PM 2016, 'A family-focused intervention for heart failure self-care: conceptual underpinnings of a culturally appropriate intervention', Journal of Advanced Nursing, vol. 72, no. 2, pp. 434-450.View/Download from: Publisher's site
Deek, HA, Newton, PJ, Noureddine, S, Inglis, SC, Kabbani, S, Macdonald, P, Davidson, PM, Al Arab, G, Chalak, W & Nadim, T 2016, 'Protocol for a block randomised controlled trial of an intervention to improve heart failure care', Nurse Researcher, vol. 23, no. 4, pp. 24-29.View/Download from: Publisher's site
Aim To describe the design of a randomised controlled trial conducted to evaluate a culturally tailored, nurse-led educational intervention.
Background Self-care strategies are critical to improving health outcomes in heart failure. The family unit is crucial in collectivist cultures, but little is known about involving the family in the self-care of patients with heart failure.
Discussion Involving the family in the self-care of heart failure is a novel approach. To the authors' knowledge, no one has evaluated it using a randomised controlled trial.
Conclusion A valid comparison of outcomes between the control group and the intervention group involved in the study was provided in this trial. The chosen design, randomised controlled trial, enabled the assessment of the intervention.
Implications for practice The application of a family self-care intervention in a collectivist culture was shown to improve clinical and quality outcomes of patients with heart failure. Considering the individual and the community needs is vital in improving these outcomes.
Deek, H, Chang, S, Noureddine, S, Newton, PJ, Inglis, SC, Macdonald, PS, Al Arab, G & Davidson, PM 2016, 'Translation and validation of the Arabic version of the Self-care of Heart Failure Index', NURSE RESEARCHER, vol. 24, no. 2, pp. 34-40.View/Download from: Publisher's site
Gholizadeh, L, Kang, K, Inglis, SC & Han, H-R 2016, 'Interventions that improve health-related quality of life in patients with myocardial infarction', Quality of Life Research, vol. 25, no. 11, pp. 2725-2737.View/Download from: Publisher's site
Patients with myocardial infarction (MI) often report lower health-related quality of life (HRQoL) than those without MI. Interventions can affect HRQoL of these patients. The purpose of this review was to identify effective strategies for improving HRQoL among individuals with MI.
Three electronic databases were searched and limited to articles peer-reviewed and published in English between 1995 and 2015. We screened titles and abstracts of the retrieved articles for studies that examined effectiveness of interventions to improve HRQoL in patients with MI.
Twenty-three studies were found that examined the effects of behavioural interventions—cardiac rehabilitation programmes (CRP), education and counselling programmes, and other psychological and cognitive interventions—to improve HRQoL in patients with MI. The studies included were mainly randomised controlled trials (14 studies) with a wide age range of participants (18–80 years) and a mean age group of 50–70 years. CRPs, including home- and hospital-based CRPs, regular weekly aerobic training programmes, and group counselling mostly resulted in improvement of HRQoL in patients with MI.
Most CRPs and other interventions were beneficial to MI patients. Therefore, patients with MI should be encouraged to participate in programmes that can help promote their HRQoL.
Deek, H, Hamilton, S, Brown, N, Inglis, SC, DiGiacomo, M, Newton, P, Noureddine, S, Macdonald, P, Davidson, PM & FAMILY Project Investigators 2016, 'Family-centred approaches to healthcare interventions in chronic diseases in adults: a quantitative systematic review.', Journal of Advanced Nursing, vol. 72, no. 5, pp. 968-979.View/Download from: Publisher's site
Increasingly there is a focus on self-care strategies for both malignant and non-malignant conditions. Models of self-care interventions have focussed on the individual and less on the broader context of family and society. In many societies, decision-making and health seeking behaviours, involve family members.To identify elements of effective family-centred self-care interventions that are likely to improve outcomes of adults living with chronic conditions.Review paper.MEDLINE (Ovid), CINAHL, Academic Search Complete, PsychInfo and Scopus between 2000-2014.Quantitative studies targeting patient outcomes through family-centred interventions in adults were retrieved using systematic methods in January, 2015. Search terms used were: 'family', 'spouse', 'carer', 'caregiver', 'chronic', 'chronic disease', 'self-care', 'self-management' and 'self-efficacy'. Reference lists were reviewed. Risk of bias assessment was performed using the Cochrane Collaboration's tool. Data were reported using a narrative summary approach.Ten studies were identified. Improvements were noted in readmission rates, emergency department presentations, and anxiety levels using family-centred interventions compared with controls. Elements of effective interventions used were a family-centred approach, active learning strategy and transitional care with appropriate follow-up.Involving the family in self-care has shown some positive results for patients with chronic conditions. The benefits of family-centred care may be more likely in specific socio-cultural contexts.The review has year limits and further research needs to identify support for both the patients and family caregivers.
Ferguson, C, Inglis, SC, Newton, PJ, Middleton, S, Macdonald, PS & Davidson, PM 2016, 'Education and practice gaps on atrial fibrillation and anticoagulation: a survey of cardiovascular nurses', BMC Medical Education, vol. 16, no. 9.View/Download from: Publisher's site
Patients' knowledge of their atrial fibrillation (AF) and anticoagulation therapy are determinants of the efficacy of thromboprophylaxis. Nurses may be well placed to provide counselling and education to patients on all aspects of anticoagulation, including self-management. It is important that nurses are well informed to provide optimal education to patients. Current practice and knowledge of cardiovascular nurses on AF and anticoagulation in the Australian and New Zealand (ANZ) context is not well reported.
This study aimed to; 1) Explore the nurse's role in clinical decision making in anticoagulation in the setting of AF; 2) Describe perceived barriers and enablers to anticoagulation in AF; 3) Investigate practice patterns in the management of anticoagulation in the ANZ setting; 4) Assess cardiovascular nurses' knowledge of anticoagulation.
A paper-based survey on current practices and knowledge of AF and anticoagulation was distributed during the Australian Cardiovascular Nursing College (ACNC) Annual Scientific Meeting, February 2014. This survey was also emailed to Cardiovascular Trials Nurses throughout New South Wales, Australia and nursing members of the Cardiac Society of Australia and New Zealand (CSANZ).
There were 41/73 (56 %) respondents to the paper-based survey. A further 14 surveys were completed online via nurse members of the CSANZ, and via an investigator developed NSW cardiovascular trials nurse email distribution list. A total of 55 surveys were completed and included in analyses. Prior education levels on AF, stroke risk, anticoagulation and health behaviour modification were mixed. The CHA2DS2VASc and HAS-BLED risk stratification tools were reported to be underused by this group of clinicians. Reported key barriers to anticoagulation included; fears of patients falling, fears of poor adherence to medication taking and routine monitoring. Patient self-monitoring and self-management were reported as underutilise...
Inglis, S, Clark, RA, Dierckx, R, Prieto-Merino, D & Cleland, JGF 2015, 'Structured telephone support or non-invasive telemonitoring for patients with heart failure', Cochrane Database of Systematic Reviews, no. 10, pp. 1-4.View/Download from: Publisher's site
We reviewed the evidence about the effect of structured telephone support and non-invasive telemonitoring in the management of people with heart failure. We found 41 studies. Two of the included studies trialled both structured telephone support and telemonitoring compared to usual care, therefore 43 comparisons are evident. The evidence is current to January 2015.
In the context of limited health funding and a rapidly expanding population of older people, it is increasingly difficult for healthcare systems to provide high-quality care to those with heart failure. Multidisciplinary specialist heart failure clinics are available only to a minority of people and do not have the capacity for frequent patient review. Patients may be unwilling or unable to make frequent clinic attendance due to cost, difficulty with transport or disability and frailty. Structured telephone support and telemonitoring can provide specialised heart failure care to a large number of people with limited access to healthcare services.
We include 41 full-text peer-reviewed studies of either structured telephone support or home telemonitoring in this review. Twenty-five studies evaluate structured telephone support (eight new studies, plus one previously included study now classified as telemonitoring; total of 9332 participants), 18 evaluated telemonitoring (nine new studies; total of 3860 participants) and two studies evaluated both interventions (included in listed counts).
This review demonstrates that supporting people with heart failure at home using information technology can reduce the rates of death and heart failure-related hospitalisation. It can improve people's quality of life and knowledge about heart failure and self care. Most patients, even those who are elderly, learn to use the technology easily and are satisfied with these interventions.
Inglis, S, Conway, A, Cleland, JG & clark, R 2015, 'Is age a factor in the success or failure of remote monitoring in heart failure? Telemonitoring and structured telephone support in elderly heart failure patients', European Journal of Cardiovascular Nursing, vol. 14, no. 3, pp. 248-255.View/Download from: Publisher's site
Inglis, SC & Clark, RA 2015, 'A systematic approach to chronic heart failure care: a consensus statement', MEDICAL JOURNAL OF AUSTRALIA, vol. 202, no. 7, pp. 361-+.View/Download from: Publisher's site
Deek, HA, Newton, PJ, Inglis, S, Kabbani, S, Noureddine, S, Macdonald, P & Davidson, PM 2015, 'Heart health in Lebanon and considerations for addressing the burden of cardiovascular disease.', Collegian, vol. 22, no. 3, pp. 333-339.View/Download from: Publisher's site
To (1) aggregate and define the burden of cardiovascular disease in Lebanon and (2) describe implications for policy, practice and research to improve health outcomes in Lebanon.
Inglis, SC, Du, H, Dennison Himmelfarb, C & Davidson, PM 2015, 'mHealth education interventions in heart failure', Cochrane Database of Systematic Reviews, vol. 2015, no. 8.View/Download from: Publisher's site
© 2015 The Cochrane Collaboration. This is the protocol for a review and there is no abstract. The objectives are as follows: To systematically review and quantify the potential benefits of mHealth education for people with heart failure.
Disler, R, Inglis, S, Newton, P, Currow, D, Macdonald, P, Glanville, A, Donesky, D, Carrieri-Kohlman, V & Davidson, P 2015, 'ATTITUDES TO ONLINE DELIVERY OF HEALTH INFORMATION AND CHRONIC DISEASE MANAGEMENT IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: FOCUS GROUP STUDY', Respirology, vol. 20, pp. 105-105.
Disler, R, Inglis, S, Newton, P, Currow, D, Macdonald, P, Glanville, A, Donesky, D, Carrieri-Kohlman, V & Davidson, P 2015, 'USE OF TECHNOLOGY IN CARDIOPULMONARY PATIENTS', Respirology, vol. 20, pp. 13-13.
Disler, R, Spiliopoulos, N, Inglis, S, Currow, D & Davidson, P 2015, 'INDIVIDUALS ATTITUDES TO COGNITIVE IMPAIRMENT AND IMPACT IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: FOCUS GROUP STUDY', RESPIROLOGY, vol. 20, pp. 105-105.
Disler, RT, Inglis, SC, Newton, PJ, Currow, DC, Macdonald, PS, Glanville, AR, Donesky, D, Carrieri-Kohlman, V & Davidson, PM 2015, 'Patterns of Technology Use in Patients Attending a Cardiopulmonary Outpatient Clinic: A Self-Report Survey', Interactive Journal of Medical Research, vol. 4, no. 1, pp. 1-14.View/Download from: Publisher's site
Background: Self-management education for cardiopulmonary diseases is primarily provided through time-limited, face-to-face programs, with access limited to a small percentage of patients. Telecommunication tools will increasingly be an important component of future health care delivery.
Objective: The purpose of this study was to describe the patterns of technology use in patients attending a cardiopulmonary clinic in an academic medical center.
Methods: A prevalence survey was developed to collect data on participant demographics (age in years, sex, and socioeconomic status); access to computers, Internet, and mobile phones; and use of current online health support sites or programs. Surveys were offered by reception staff to all patients attending the outpatient clinic.
Results: A total of 123 surveys were collected between March and April 2014. Technological devices were a pervasive part of everyday life with respondents engaged in regular computer (102/123, 82.9%), mobile telephone (115/117, 98.3%), and Internet (104/121, 86.0%) use. Emailing (101/121, 83.4%), researching and reading news articles (93/121, 76.9%), social media (71/121, 58.7%), and day-to-day activities (65/121, 53.7%) were the most common telecommunication activities. The majority of respondents reported that access to health support programs and assistance through the Internet (82/111, 73.9%) would be of use, with benefits reported as better understanding of health information (16/111, 22.5%), avoidance of difficult travel requirements and time-consuming face-to-face appointments (13/111, 18.3%), convenient and easily accessible help and information (12/111, 16.9%), and access to peer support and sharing (9/111, 12.7%). The majority of patients did not have concerns over participating in the online environment (87/111, 78.4%); the few concerns noted related to privacy and security (10/15), information accuracy (2/15), and computer literacy and access (2/15).
Conclusions: Chronic disease bur...
Disler, RT, Inglis, SC, Newton, PJ, Currow, DC, Macdonald, PS, Glanville, AR, Donesky, D, Carrieri-Kohlman, V & Davidson, PM 2015, 'Patterns of Technology Use in Patients Attending a Cardiopulmonary Outpatient Clinic: A Self-Report Survey', JOURNAL OF MEDICAL INTERNET RESEARCH, vol. 17, no. 3.
Spiliopoulos, N, Inglis, SC, Currow, DC, Davidson, PM & Disler, RT 2015, 'Attitudes To Cognitive Impairment And Testing In Patients With Chronic Obstructive Pulmonary Disease: Focus Group Study', Am J Respir Crit Care Med, vol. 191, pp. A5291-A5291.
Allida, SM, Inglis, SC, Davidson, PM, Lal, S, Hayward, CS & Newton, PJ 2015, 'Thirst in chronic heart failure: a review.', Journal of clinical nursing, vol. 24, no. 7-8, pp. 916-926.View/Download from: Publisher's site
This review will (1) explore factors related to thirst in chronic heart failure and (2) describe interventions to alleviate thirst in chronic heart failure patients.Thirst is a common and troublesome symptom of chronic heart failure. Despite the burden and prevalence of this symptom, there are limited strategies to assist in its management.This is a review of literature on the burden of thirst, contributors to thirst and potential management strategies of thirst in patients with chronic heart failure.Medline, Cumulative Index for Nursing and Allied Health, PubMed and Scopus were searched using the key words thirst, chronic heart failure, angiotensin II, fluid restriction and intervention. Of the 165 citations yielded, nine studies (n = 9) were included. The eligibility criteria included participants with confirmed diagnosis of chronic heart failure, randomised controlled studies or any studies with thirst as primary or secondary outcome, in humans and in English. There was no limit to the years searched.Factors related to thirst in chronic heart failure were condition; prolonged neurohormonal activation, treatment; pharmacological interventions and fluid restriction and emotion. No intervention studies were found in chronic heart failure patients. Interventions such as artificial saliva and chewing gum have been investigated for their effectiveness as a thirst reliever in haemodialysis patients.Thirst is a frequent and troublesome symptom for individuals with chronic heart failure. It is highly likely that this contributes to poor adherence with fluid restrictions. Chewing gum can help alleviate thirst, but investigation in people with heart failure is needed.Increasing awareness of thirst and interventions to relieve it in clinical practice is likely to improve the quality of care for people with chronic heart failure.
Ferguson, C, Inglis, S, Newton, PJ, Middleton, S, Macdonald, P & Davidson, PM 2015, 'The caregiver role in thromboprophylaxis management in atrial fibrillation: A literature review', European Journal of Cardiovascular Nursing, vol. 14, no. 2, pp. 98-107.View/Download from: Publisher's site
Background: Atrial fibrillation is a common arrhythmia and a risk factor for adverse events including stroke. People living with atrial fibrillation are commonly elderly and have multiple comorbidities. The role of a caregiver in supporting the individual to manage a chronic and complex condition has received limited attention.
Conway, A, Inglis, S & Clark, R 2014, 'Effective technologies for noninvasive remote monitoring in heart failure', Telemedicine and e-health, vol. 20, no. 6, pp. 531-538.View/Download from: Publisher's site
Background: Trials of new technologies to remotely monitor for signs and symptoms of worsening heart failure are continually emerging. The extent to which technological differences impact the effectiveness of noninvasive remote monitoring for heart failure management is unknown. This study examined the effect of specific technology used for noninvasive remote monitoring of people with heart failure on all-cause mortality and heart failurerelated hospitalizations.
Allida, SM, Inglis, SC, Davidson, PM, Hayward, CS & Newton, PJ 2014, 'Measurement of thirst in chronic heart failure - A review.', Contemporary Nurse, vol. 48, no. 1, pp. 2-9.View/Download from: Publisher's site
Abstract Background: Thirst is a bothersome symptom of chronic heart failure (CHF) which impacts adversely on quality of life. Despite this, limited work has been done to investigate thirst as a symptom or to develop reliable and valid measures of thirst in CHF. The purpose of this manuscript is to establish which tools have been used in research to measure thirst in CHF.Medline, PubMed, Cumulative Index for Nursing and Allied Health, and Scopus were searched using following key words thirst, heart failure, measure, scale, randomised controlled trials and multicentre studies.The search discovered 37 studies of which 6 studies met the inclusion criteria. One study was a research abstract and five were full-text studies. To date, there are only three measurement tools utilised in studies examining thirst in CHF patients [Visual Analogue Scale (VAS), Numeric Rating Scale and Thirst Distress Scale].Thirst in CHF is measured in a non-systematic way. In recent studies, the VAS has been used to measure thirst intensity. While this measurement tool is very easy and quick to administer, using a uni-dimensional tool in conjunction with a multi-dimensional tool may be beneficial to capture all dimensions of thirst. In order to manage thirst efficiently, consistent measurement of thirst in CHF is vital.
Chang, S, Newton, PJ, Inglis, S, Luckett, T, Krum, H, MacDonald, PS & Davidson, PM 2014, 'Are all outcomes in chronic heart failure rated equally? An argument for a patient-centred approach to outcome assessment', Heart Failure Reviews, vol. 19, no. 2, pp. 153-162.View/Download from: Publisher's site
Chronic heart failure (CHF) is a multi-dimensional and complex syndrome. Outcome measures are important for determining both the efficacy and quality of care and capturing the patient's perspective in evaluating the outcomes of health care delivery. Capturing the patient's perspective via patient-reported outcomes is increasingly important; however, including objective measures such as mortality would provide more complete account of outcomes important to patients. Currently, no single measure for CHF outcomes captures all dimensions of the quality of care from the patient's perspective.
Disler, RT, Green, AR, Luckett, T, Newton, PJ, Inglis, S, Currow, D & Davidson, PM 2014, 'Experience of advanced chronic obstructive pulmonary disease: Metasynthesis of qualitative data.', Journal of Pain and Symptom Management, vol. 48, no. 6, pp. 1182-1199.View/Download from: Publisher's site
Context. Chronic obstructive pulmonary disease (COPD) is a life-limiting illness. Despite best available treatments, individuals continue to experience symptom burden and have high health-care utilization. Objectives. To increase understanding of the experience and ongoing needs of individuals living with COPD.
Ferguson, C, Inglis, S, Newton, PJ, Cripps, PJ, Macdonald, P & Davidson, PM 2014, 'Social media: A tool to spread information: A case study analysis of Twitter conversation at the Cardiac Society of Australia & New Zealand 61st Annual Scientific Meeting 2013', Collegian, vol. 21, no. 2, pp. 89-93.View/Download from: Publisher's site
Background The World Wide Web has changed the way in which people communicate and consume information. More importantly, this innovation has increased the speed and spread of information. There has been recent increase in the percentage of cardiovascular professionals, including journals and associations using Twitter to engage with others and exchange ideas. Evaluating the reach and impact in scientific meetings is important in promoting the use of social media. Objective This study evaluated Twitter use during the recent 61st Annual Scientific Meeting at the Cardiac Society of Australia and New Zealand. Methods During the Cardiac Society of Australia and New Zealand 2013 61st Annual Scientific Meeting Symplur was used to curate conversations that were publicly posted with the hashtag #CSANZ2013. The hashtag was monitored with analysis focused on the influencers, latest tweets, tweet statistics, activity comparisons, and tweet activity during the conference. Additionally, Radian6 social media listening software was used to collect data. A summary is provided. Results There were 669 total tweets sent from 107 unique Twitter accounts during 8th August 9 a.m. to 11th August 1 p.m. This averaged nine tweets per hour and six tweets per participant. This assisted in the sharing of ideas and disseminating the findings and conclusions from presenters at the conference with a total 1,432,573 potential impressions in Twitter users tweet streams. Conclusion This analysis of Twitter conversations during a recent scientific meeting highlights the significance and place of social media within research dissemination and collaboration. Researchers and clinicians should consider using this technology to enhance timely communication of findings. The potential to engage with consumers and enhance shared decision-making should be explored further.
Ferguson, C, Inglis, S, Newton, PJ, Middleton, S, MacDonald, PS & Davidson, PM 2014, 'Atrial Fibrillation: Stroke Prevention in Focus', Australian Critical Care, vol. 27, no. 2, pp. 92-98.View/Download from: Publisher's site
Introduction: Atrial fibrillation (AF) is a common arrhythmia and a risk factor for stroke and other adverse events. Internationally there have been recent advancements in the therapies available for stroke prevention in AF. Nurses will care for individuals with AF across a variety of primary and acute care settings and should be familiar with evidence based therapies. Aim: This paper provides a review of the epidemiology of AF and stroke, stroke and bleeding risk assessment tools and evidence based treatments for the prevention of stroke in AF including the use of novel anti-thrombin agents. Method: A review of key databases was conducted from 2002 - 2012 using the key search terms 'atrial fibrillation' 'anticoagulation' 'risk assessment' and 'clinical management'. The following electronic databases were searched: CINAHL, Medline, Scopus, the Cochrane Library and Google Scholar. Reference lists were manually hand searched. Key clinical guidelines from National Institute for Clinical Excellence (NICE, UK), American Heart Association (AHA, USA), American College of Cardiology (ACC, USA) and the European Society of Cardiology (ESC) and key government policy documents were also included. Articles were included in the review if they addressed nursing management with a focus on Australia. Results: Many treatment options exist for AF. Best practice guidelines make a variety of recommendations which include cardioversion, ablation, pulmonary vein isolation, pharmacological agents for rate or rhythm control approaches, and antithrombotic therapy (including anticoagulation and antiplatelet therapy). Treatment should be patient centred and individualised based upon persistency of the rhythm, causal nature, risk and co-morbid conditions. Conclusion: AF is a common and burdensome condition where treatment is complex and not without risk. Nurses will encounter individuals with AF across a variety of primary and acute care areas understanding the risk of AF and appropriate...
Conway, A, Inglis, S, Chang, A, Horton-Breshears, M, Cleland, JG & Clark, R 2013, 'Not all systematic reviews are systematic: a meta-review of the quality of systematic reviews for non-invasive remote monitoring in heart failure', Journal of Telemedicine Telecare, vol. 19, no. 6, pp. 326-337.View/Download from: Publisher's site
We carried out a critical appraisal and synthesis of the systematic reviews and meta-analyses of remote monitoring for heart failure. A comprehensive literature search identified 65 relevant publications from 3333 citations. Seventeen studies fulfilled the inclusion and exclusion criteria. Seven (41%) systematic reviews pooled results for meta-analysis. Eight (47%) considered all non-invasive remote monitoring strategies. Five (29%) focused on telemonitoring. Four (24%) included both non-invasive and invasive technologies. The reviews were appraised by two independent reviewers for their quality and risk of bias using the AMSTAR tool. According to the AMSTAR criteria, ten (58%) systematic reviews were of poor methodological quality. In the high quality reviews, the relative risk of mortality in patients who received remote monitoring ranged from 0.53 to 0.88. The high quality reviews also reported that remote monitoring reduced the relative risk of all-cause (0.52 to 0.96) and heart failure-related hospitalizations (0.72 to 0.79) and, as a consequence, healthcare costs. However, further research is required before considering widespread implementation of remote monitoring. The subset of the heart failure population that derives the most benefit from intensive monitoring, the best technology, and the optimum duration of monitoring, all need to be identified.
Inglis, S, Bebchuk, J, Al-Suhaim, SA, Case, J, Pfeffer, MA, Solomon, SD, Hou, Y, Pitt, B, Dargie, HJ, Ford, I, Kjekshus, J, Zannad, F, Dickstein, K & McMurray, JJ 2013, 'Peripheral artery disease and outcomes after myocardial infarction: An individual-patient meta-analysis of 28,771 patients in CAPRICORN, EPEHESUS, OPTIMAAL and VALIANT', International Journal Of Cardiology, vol. 168, no. 2, pp. 1094-1101.View/Download from: Publisher's site
OBJECTIVES: To examine the prevalence of peripheral artery disease (PAD) and the relationship between PAD and cardiovascular (CV) outcomes in subjects with left ventricular systolic dysfunction, heart failure or both after acute myocardial infarction (MI).
Inglis, S, Lewsey, J, Lowe, GD, Jhund, P, Gillies, M, Stewart, S, Capewell, S, MacIntyre, K & McMurray, JJ 2013, 'Angina and intermittent claudication in 7403 participants of the 2003 Scottish Health Survey: Impact on general and mental health, quality of life and five-year mortality', International Journal Of Cardiology, vol. 167, no. 5, pp. 2149-2155.View/Download from: Publisher's site
Background Angina and intermittent claudication impair function and mobility and reduce health-related quality of life. Both symptoms have similar etiology, yet the physical and psychological impacts of these symptoms are rarely studied in community-based cohorts or in individuals with isolated symptoms.
Davidson, PM, Inglis, S & Newton, PJ 2013, 'Self-care In Patients With Chronic Heart Failure', Expert Review of Pharmacoeconomics & Outcomes Research, vol. 13, no. 3, pp. 351-359.View/Download from: Publisher's site
Globally, chronic heart failure is a common, complex syndrome characterized by high levels of healthcare utilization, reduced quality of life and premature mortality. Self-care is a complex decision-making process involving symptom recognition, action and evaluation.
Disler, RT, Inglis, S & Davidson, PM 2013, 'Non-pharmacological management interventions for COPD: an overview of Cochrane systematic reviews (Protocol)', The Cochrane Database of Systematic Reviews, vol. 2, pp. 1-8.View/Download from: Publisher's site
summarise the evidence, b) identify gaps in the evidence base and c) describe elements of non-pharmacological, non-surgical and non-device interventions for the management of COPD using a standardised taxonomy for disease management adapted from the American Heart Association (Krumholz 2006).
Inglis, S, Hermis, A, Shehab, S, Newton, PJ, Lal, S & Davidson, PM 2013, 'Peripheral arterial disease and chronic heart failure: a dangerous mix', Heart Failure Reviews, vol. 18, no. 4, pp. 457-464.View/Download from: Publisher's site
Chronic heart failure (CHF) is associated with a high comorbidity burden, adverse impact on quality of life and high health care utilisation. Peripheral arterial disease (PAD) and CHF share many risk, pathophysiological and prognostic features, and each has been associated with increased morbidity and mortality. PAD often goes undetected, and yet in spite of the availability of screening tools, this is not commonly considered in CHF care. A review of the electronic databases Medline, CINAHL and Cochrane CENTRAL was undertaken using the MeSH terms peripheral arterial disease, peripheral vascular disease, intermittent claudication and heart failure to identify studies examining the prevalence and clinical outcomes of coexisting PAD in patients with CHF. Five studies were identified. There are limited data describing the impact of PAD on CHF outcomes. As PAD may contribute to decreased capacity to exercise and other self-care behaviours, identifying those at risk and providing appropriate therapy are important. Based on this review, patients who are smokers and those with diagnosed coronary heart disease and diabetes should be targeted for the screening of PAD.
Ferguson, C, Inglis, S, Newton, PJ, Middleton, S, Macdonald, P & Davidson, PM 2013, 'Atrial fibrillation and thromboprophylaxis in heart failure: The need for patient centered approaches to address adherence', Vascular Health and Risk Management, vol. 9, pp. 3-11.View/Download from: Publisher's site
Atrial fibrillation is a common arrhythmia in heart failure and a risk factor for stroke. Risk assessment tools can assist clinicians with decision-making in the allocation of thromboprophylaxis. This review provides an overview of current validated risk assessment tools for AF and emphasises the importance of addressing both tailoring individual risk for stroke and weighing the benefits of treatment. Further, this review provides details of innovative and patient centered methods for ensuring optimal adherence to prescribed therapy. Prior to initiating oral anticoagulant therapy a comprehensive risk assessment should include evaluation of associated cardio-geriatric conditions, potential for adherence to prescribed therapy, frailty, functional and cognitive ability.
Inglis, S, Lewsey, J, Chandler, D, Byrne, D, Lowe, GD, MacIntyre, K & Peripheral Artery Disease Project Advisory Group 2012, 'Sex-specific time trends in first admission to hospital for peripheral artery disease in Scotland 1991- 2007', British Journal of Surgery, vol. 99, no. 5, pp. 680-687.View/Download from: Publisher's site
Background: This study examined trends for all first hospital admissions for peripheral artery disease (PAD) in Scotland from 1991 to 2007 using the Scottish Morbidity Record. Methods: First admissions to hospital for PAD were defined as an admission to hospital (inpatient and day-case) with a principal diagnosis of PAD, with no previous admission to hospital (principal or secondary diagnosis) for PAD in the previous 10 years. Results: From 1991 to 2007, 41 593 individuals were admitted to hospital in Scotland for the first time for PAD. Some 23 016 (55·3 per cent) were men (mean(s.d.) age 65·7(11·7) years) and 18 577 were women (aged 70·4(12·8) years). For both sexes the population rate of first admissions to hospital for PAD declined over the study interval: from 66·7 per 100 000 in 1991-1993 to 39·7 per 100 000 in 2006-2007 among men, and from 43·5 to 29·1 per 100 000 respectively among women. After adjustment, the decline was estimated to be 42 per cent in men and 27 per cent in women (rate ratio for 2007 versus 1991: 0·58 (95 per cent confidence interval 0·55 to 0·62) in men and 0·73 (0·68 to 0·78) in women). The intervention rate fell from 80·8 to 74·4 per cent in men and from 77·9 to 64·9 per cent in women. The proportion of hospital admissions as an emergency or transfer increased, from 23·9 to 40·7 per cent among men and from 30·0 to 49·5 per cent among women. Conclusion: First hospital admission for PAD in Scotland declined steadily and substantially between 1991 and 2007, with an increase in the proportion that was unplanned.
Disler, R, Inglis, SC, Currow, DC & Davidson, PM 2012, 'Palliative and Supportive Care in Chronic Obstructive Pulmonary Disease: Research Priorities to Decrease Suffering', Open Access Scientific Reports, vol. 1, no. 6, pp. 1-3.View/Download from: Publisher's site
Chronic obstructive pulmonary disease (COPD) affects 80 million people worldwide, is the fourth most prevalent
cause of death globally and accounts for 3.5% of total years lost due to disability. Despite the similarities with
malignant disease, many individuals suffer unnecessarily and continue to have limited access to palliative and endof-life
care. Changing this will require a shift in focus and approach as well as support for clinical decision making.
Lack of communication regarding care plans and prognosis and coordination across care settings has been identified
as barriers to end-of-life care. Research specifically should focus on improving the use of comprehensive and
collaborative approaches to end-stage COPD care such as those illustrated in the Chronic Care Model which has
demonstrated improved outcomes for chronic conditions. Revision of funding models and workforce organisation,
aided by clinical pathways may improve end of life care for COPD.
Davidson, PM, Mitchell, J, DiGiacomo, M, Inglis, S, Newton, PJ, Harman, J & Daly, J 2012, 'Cardiovascular disease in women: implications for improving health outcomes', Collegian, vol. 19, no. 1, pp. 5-13.View/Download from: Publisher's site
This literature review collated data on women and cardiovascular disease in Australia and globally to inform public health campaigns and health care interventions. If found that women with acute coronary syndromes show consistently poorer outcomes than men, independent of comorbidity and management, despite less anatomical obstruction of coronary arteries and relatively preserved left ventricular function. Higher mortality and complication rates are best documented amongst younger women and those with STsegment-elevation myocardial infarction. Sex differences in atherogenesis and cardiovascular adaptation have been hypothesised, but not proven. Atrial fibrillation carries a relatively greater risk of stroke in women than in men, and anticoagulation therapy is associated with higher risk of bleeding complications. The degree of risk conferred by single cardiovascular risk factors and combinations of risk factors may differ between the sexes, and marked postmenopausal changes are seen in some risk factors. Sociocultural factors, delays in seeking care and differences in self-management behaviours may contribute to poorer outcomes in women. Differences in clinical management for women, including higher rates of misdiagnosis and less aggressive treatment, have been reported, but there is a lack of evidence to determine their effects on outcomes, especially in angina. Although enrolment of women in randomised clinical trials has increased since the 1970s, women remain underrepresented in cardiovascular clinical trials. Improvement in the prevention and management of CVD in women will require a deeper understanding of womenâs needs by the community, health care professionals, researchers and government.
Inglis, S, Du, H, Newton, P, DiGiacomo, M, Omari, A & Davidson, PM 2012, 'Disease management interventions for improving self-management in lower-limb peripheral arterial disease', Cochrane Database of Systematic Reviews, no. 3.View/Download from: Publisher's site
Disler, RT, Green, AR, Luckett, T, Newton, PJ, Inglis, S, Currow, D & Davidson, PM 2012, 'Unmet needs in chronic obstructive pulmonary disease: a metasynthesis protocol', International Journal of Research in Nursing, vol. 3, no. 1, pp. 15-20.View/Download from: Publisher's site
Abstract: Problem statement: Chronic obstructive pulmonary disease is a chronic progressive illness. Despite the high burden experienced by individuals in the advanced stages of illness, individuals with advanced COPD continue to have unmet needs and limited access to palliative care. This Metasynthesis seeks to describe: the barriers and facilitators care access and provision; the unmet needs of individuals with advanced COPD, their families and carers; and the experiences of health professionals. Data sources: Medline, PsychINFO, AMED, CINAHL and Sociological Abstracts were searched for articles published between 1990 and December 31st 2011. Medical Subject Headings (MeSH) and key words will be used to guide the search. The strategy will be reviewed by the CareSearch palliative knowledge network and a health informatics expert. Approach: Metasyntheses are increasingly used to gain new insights and understandings of complex research questions through the amalgamation of data from individual qualitative studies. The principles of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and thematic synthesis will be used to achieve consistent reporting and transparency of methods. Results: Inclusion of studies, quality assessment and allocation of free codes into EPPI-Reviewer 4 software will be carried out by two independent investigators. Auditing of random cases will be undertaken and disagreements resolved through group discussion of an expert panel. Descriptive and analytical themes will be developed through thematic synthesis and expert panel discussion. Conclusion: Qualitative data provide useful information in understanding the individual's unique experience. Combining discrete qualitative studies provides an important opportunity to provide a voice to patients, their families and professional careers in managing advanced COPD.
Inglis, S, Clark, R, McAlister, F, Stewart, S & Cleland, JG 2011, 'Telemedicine and remote management of heart failure. Letter to the Editor.', The Lancet, vol. 378.
Inglis, S, clark, RA & Cleland, JG 2011, 'Telemonitoring in patients with heart failure. Letter to the Editor', New England Journal Of Medicine, vol. 364.
Inglis, S, clark, RA, McAlister, F, Stewart, S & Cleland, JG 2011, 'Which components of heart failure programmes are effective? A systematic review and meta-analysis of the outcomes of structured telephone support or telemonitoring as the primary component of chronic heart failure management in 8,323 patients (Abridg', European Journal of Heart Failure, vol. 13.
Chronic heart failure (CHF) specialized disease management programmes improve survival and quality of life, reduce rehospitalization, and increase the implementation of evidence-based practice [1,2] However, most of the successful CHF disease management programmes have been built around close clinical follow-up. The need for intense face-to-face follow-up strategies limits the number of patients who can participate in these programmes.
Inglis, S, Stewart, S, Papachan, A, Vaghela, V, Libhaber, C, Veriava, Y & Sliwa, K 2011, 'Anaemia and renal function in heart failure due to idiopathic dilated cardiomyopathy', European Journal of Heart Failure, vol. 9.View/Download from: Publisher's site
To investigate the frequency of anaemia and renal dysfunction and the relationship between the two within a cohort of 163 newly diagnosed Black African idiopathic cardiomyopathy patients prior to commencing HF treatments and compare those findings to those of western HF cohorts
Inglis, SC, Clark, RA & Cleland, JGF 2011, 'Telemonitoring in Patients with Heart Failure', NEW ENGLAND JOURNAL OF MEDICINE, vol. 364, no. 11, pp. 1078-1079.
Inglis, S 2010, 'Structured telephone support or telemonitoring programmes for patients with chronic heart failure.', Journal of Evidence-Based Medicine, vol. 3.
Inglis, S, clark, RA, McAlister, F, Ball, J, LeWinter, C, Cullington, D, Stewart, S & Cleland, JG 2010, 'Structured telephone support or telemonitoring programs for patients with chronic heart failure', The Cochrane Database of Systematic Reviews, vol. 8, pp. 1-138.View/Download from: Publisher's site
Background Specialised disease management programmes for chronic heart failure (CHF) improve survival, quality of life and reduce healthcare utilisation. The overall efficacy of structured telephone support or telemonitoring as an individual component of a CHF disease management strategy remains inconclusive.
Inglis, S, clark, RA, McAlister, F, Ball, J, LeWinter, C, Cullington, D, Stewart, S & Cleland, JG 2010, 'Structured telephone support or telemonitoring programs for patients with chronic heart failure (Review).', The Cochrane Database of Systematic Reviews, vol. 8, pp. 228-228.View/Download from: Publisher's site
Chronic heart failure is a debilitating condition, which can lead to frequent stays in hospital and shortened life expectancy. In recent years, a variety of ways to strengthen self-management and education interventions have been researched and developed. The most successful strategies involve specialist multidisciplinary disease management programs but many patients with heart failure don't have access to these specialist services. This is either because of limited healthcare resources and services, or difficulty in attending the management programmes because of distance or disability.
Inglis, S, McMurray, JJ, Bohm, V, Schaufelberger, M, van Veldhuisen, D, Lindberg, M, Dunselman, P, Hjalmarson, A, Kjekshus, J, Waagstein, F, Wedel, H & Wikstrand, J 2010, 'Intermittent claudication as a predictor of outcome in patients with ischemic systolic heart failure: analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure trial (CORONA).', European Journal of Heart Failure, vol. 12, no. 7, pp. 698-705.View/Download from: Publisher's site
To examine the relationship between baseline intermittent claudication and outcomes in patients enrolled in the Controlled Rosuvastatin Multinational Trial in Heart Failure trial (CORONA). Intermittent claudication is an independent predictor of worse outcome in coronary heart disease, but its prognostic importance in heart failure (HF) is unknown. Patients aged .60 years with NYHA class II-IV, low ejection fraction HF of ischaemic aetiology were enrolled in CORONA. Rosuvastatin did not reduce the primary outcome or all-cause mortality.
Inglis, S, Clark, RA, Cleland, JG, McAlister, F & Stewart, S 2008, 'Structured telephone support or telemonitoring programs for patients with chronic heart failure (Protocol)', The Cochrane Database of Systematic Reviews, vol. 3, pp. 1-12.View/Download from: Publisher's site
Chronic heart failure (CHF) is a complex, debilitating syndrome which is the consequence of structural abnormality or cardiac dysfunction that impairs the ability of the ventricle to ?ll with, or eject blood. As a result typical symptoms such as dyspnoea and fatigue occur at rest or with physical effort. CHF often results from damage to the myocardium for which the aetiology differs according to the population studied. In high income nations CHF is often the end-product of underlying coronary heart disease. In low to medium income nations the syndrome is often the result of longstanding hypertension, cardiomyopathy or rheumatic heart disease (Sliwa 2005). This trend is changing, with the incidence and prevalence of cardiovascular disease increasing in low to medium income nations (Yusuf 2001). CHF exerts a signi?cant burden on healthcare systems, with the majority of its economic burden attributable to repeated and lengthy admissions to hospital (Stewart 2002). As the prevalence of CHF increases with the ageing of populations internationally, this situation will deteriorate unless new management strategies are developed (Cleland 2000).
Inglis, S, clark, RA, Shakib, S, Wong, D, Molaee, P, Wilkinson, D & Stewart, S 2008, 'Hot summers and heart failure: seasonal variations in morbidity and mortality in Australian heart failure patients (1994-2005)', European Journal of Heart Failure, vol. 10, no. 6, pp. 540-549.View/Download from: Publisher's site
Background: There are minimal reports of seasonal variations in chronic heart failure (CHF)-related morbidity and mortality beyond the northern hemisphere. Aims and methods: We examined potential seasonal variations with respect to morbidity and all-cause mortality over more than a decade in a cohort of 2961 patients with CHF from a tertiary referral hospital in South Australia subject to mild winters and hot summers. Results: Seasonal variation across all event-types was observed. CHF-related morbidity peaked in winter (July) and was lowest in summer (February): 70 (95% CI: 65 to 76) vs. 33 (95% CI: 30 to 37) admissions/1000 at risk (pb0.005). All-cause admissions (113 (95% CI: 107 to 120) vs. 73 (95% CI 68 to 79) admissions/1000 at risk, pb0.001) and concurrent respiratory disease (21% vs. 12%, pb0.001) were consistently higher in winter. 2010 patients died, mortality was highest in August relative to February: 23 (95% CI: 20 to 27) vs. 12 (95% CI: 10 to 15) deaths per 1000 at risk, pb0.001. Those aged 75 years or older were most at risk of seasonal variations in morbidity and mortality. Conclusion: Seasonal variations in CHF-related morbidity and mortality occur in the hot climate of South Australia, suggesting that relative (rather than absolute) changes in temperature drive this global phenomenon.
clark, RA, Inglis, S, McAlister, F, Cleland, JG & Stewart, S 2007, 'Telemonitoring or structured telephone support programmes for patients with chronic heart failure: systematic review and meta-analysis', British Medical Journal, vol. 334, no. 942, pp. 1-9.
Objective To determine whether remote monitoring (structured telephone support or telemonitoring) without regular clinic or home visits improves outcomes for patients with chronic heart failure. Data sources 15 electronic databases, hand searches of previous studies, and contact with authors and experts. Data extraction Two investigators independently screened the results. Review methods Published randomised controlled trials comparing remote monitoring programmes with usual care in patients with chronic heart failure managed within the community. Results 14 randomised controlled trials (4264 patients) of remote monitoring met the inclusion criteria: four evaluated telemonitoring, nine evaluated structured telephone support, and one evaluated both. Remote monitoring programmes reduced the rates of admission to hospital for chronic heart failure by 21% (95% confidence interval 11% to 31%) and all cause mortality by 20% (8% to 31%); of the six trials evaluating health related quality of life three reported significant benefits with remote monitoring, and of the four studies examining healthcare costs with structured telephone support three reported reduced cost and one no effect. Conclusion Programmes for chronic heart failure that include remote monitoring have a positive effect on clinical outcomes in community dwelling patients with chronic heart failure.
Inglis, S, Herbert, MK, Davies, BJ, Coller, JK, James, HM, Horowitz, JD, Morris, RG, Milne, RW, Somogyi, AA & Sallustio, BC 2007, 'Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemia', Pharmacogenetics and Genomics, vol. 17, no. 5, pp. 305-312.
Aims: This study investigated the effects of increasing doses of rac-perhexiline maleate and CYP2D6 phenotype and genotype on the pharmacokinetics of (+) and (-)-perhexiline. Methods: In a prospective study, steady-state plasma concentrations of (+) and (-)-perhexiline were quantified in 10 CYP2D6 genotyped patients following dosing with 100 mg/day rac-perhexiline maleate, and following a subsequent dosage increase to 150 or 200 mg/day. In a retrospective study, steady-state plasma concentrations of (+) and (-)-perhexiline were obtained from 111 CYP2D6 phenotyped patients receiving rac-perhexiline maleate. Aims: This study investigated the effects of increasing doses of rac-perhexiline maleate and CYP2D6 phenotype and genotype on the pharmacokinetics of (+) and (-)-perhexiline. Methods: In a prospective study, steady-state plasma concentrations of (+) and (-)-perhexiline were quantified in 10 CYP2D6 genotyped patients following dosing with 100 mg/day rac-perhexiline maleate, and following a subsequent dosage increase to 150 or 200 mg/day. In a retrospective study, steady-state plasma concentrations of (+) and (-)-perhexiline were obtained from 111 CYP2D6 phenotyped patients receiving rac-perhexiline maleate. Conclusions: Perhexiline's pharmacokinetics exhibit significant enantioselectivity in CYP2D6 extensive/intermediate and poor metabolizers, with both enantiomers displaying polymorphic and saturable metabolism via CYP2D6. Clinical use of rac-perhexiline may be improved by developing specific enantiomer target plasma concentration ranges.
Inglis, S & Stewart, S 2006, 'Metabolic therapeutics in angina pectoris: history revisited with perhexiline', European Journal of Cardiovascular Nursing, vol. 5, no. 2, pp. 175-184.
Metabolic therapeutics in angina pectoris: history revisited with perhexiline
Inglis, S, Pearson, S, Treen, S, Gallasch, T, Horowitz, JD & Stewart, S 2006, 'Extending the horizon in chronic heart failure: effects of multidisciplinary, home-based intervention relative to usual care', Circulation, vol. 114, no. 23, pp. 2466-2473.View/Download from: Publisher's site
Background The long-term impact of chronic heart failure management programs over the typical life span of affected individuals is unknown. Methods and Results The effects of a nurse-led, multidisciplinary, home-based intervention (HBI) in a typically elderly cohort of patients with chronic heart failure initially randomized to either HBI (n=149) or usual postdischarge care (UC) (n=148) after a short-term hospitalization were studied for up to 10 years of follow-up (minimum 7.5 years of follow-up). Study end points were all-cause mortality, event-free survival (event was defined as death or unplanned hospitalization), recurrent hospital stay, and cost per life-year gained. Median survival in the HBI cohort was almost twice that of UC (40 versus 22 months; P<0.001), with fewer deaths overall (HBI, 77% versus 89%; adjusted relative risk, 0.74; 95% CI, 0.53 to 0.80; P<0.001). HBI was associated with prolonged event-free survival (median, 7 versus 4 months; P<0.01). HBI patients had more unplanned readmissions (560 versus 550) but took 7 years to overtake UC; the rates of readmission (2.04±3.23 versus 3.66±7.62 admissions; P<0.05) and related hospital stay (14.8±23.0 versus 28.4±53.4 days per patient per year; P<0.05) were significantly lower in the HBI group. HBI was associated with 120 more life-years per 100 patients treated compared with UC (405 versus 285 years) at a cost of $1729 per additional life-year gained when we accounted for healthcare costs including the HBI.
Pearson, S, Inglis, S, McLennan, S, Brennan, L, Russell, M, Wilkinson, D, Thompson, D & Stewart, S 2006, 'Prolonged effects of a home-based intervention in patients with chronic illness', Archives of Internal Medicine, vol. 166, no. 6, pp. 645-650.View/Download from: Publisher's site
Background: Data on the long-term benefits of nonspecific disease management programs are limited. We performed a long-term follow-up of a previously published randomized trial. Methods: We compared all-cause mortality and recurrent hospitalization during median follow-up of 7.5 years in a heterogeneous cohort of patients with chronic illness initially exposed to a multidisciplinary, home-based intervention (HBI) (n = 260) or to usual postdischarge care (n = 268). Results: During follow-up, HBI had no impact on all-cause mortality (relative risk, 1.04; 95% confidence interval, 0.801.35) or event-free survival from death or unplanned hospitalization (relative risk, 1.03; 95% confidence interval, 0.861.24). Initial analysis suggested that HBI had only a marginal impact in reducing unplanned hospitalization, with 677 readmissions vs 824 for the usual care group (mean ± SD rate, 0.72 ± 0.96 vs 0.84 ± 1.20 readmissions/patient per year; P = .08). When accounting for increased hospital activity in HBI patients with chronic obstructive pulmonary disease during follow-up for 2 years, post hoc analyses showed that HBI reduced readmissions by 14% within 2 years in patients without this condition (mean ± SD rate, 0.54 ± 0.72 vs 0.63 ± 0.88 readmission/patient per year; P = .04) and by 21% in all surviving patients within 3 to 8 years (mean ± SD rate, 0.64 ± 1.26 vs 0.81 ± 1.61 readmissions/patient per year; P = .03). Overall, recurrent hospital costs were significantly lower (14%) in the HBI group (mean ± SD, $823 ± $1642 vs $960 ± $1376 per patient per year; P = .045).
Inglis, S, McLennan, S, Dawson, A, Birchmore, L, Horowitz, JD, Wilkinson, D & Stewart, S 2004, 'A new solution for an old problem? Effects of a nurse-led, multidisciplinary, home-based intervention on readmission and mortality in patients with chronic atrial fibrillation.', Journal of Cardiovascular Nursing, vol. 19.
Ferguson, C, Inglis, SC, Breen, PP, Gargiulo, GD, Byiers, V, Macdonald, PS & Hickman, LD, 'Clinician Perspectives on the Design and Application of Wearable Cardiac Technologies for Older Adults: Qualitative Study (Preprint)'.View/Download from: Publisher's site
New wearable devices (for example, AliveCor or Zio patch) offer promise in detecting arrhythmia and monitoring cardiac health status, among other clinically useful parameters in older adults. However, the clinical utility and usability from the perspectives of clinicians is largely unexplored.
This study aimed to explore clinician perspectives on the use of wearable cardiac monitoring technology for older adults.
A descriptive qualitative study was conducted using semistructured focus group interviews. Clinicians were recruited through purposive sampling of physicians, nurses, and allied health staff working in 3 tertiary-level hospitals. Verbatim transcripts were analyzed using thematic content analysis to identify themes.
Clinicians representing physicians, nurses, and allied health staff working in 3 tertiary-level hospitals completed 4 focus group interviews between May 2019 and July 2019. There were 50 participants (28 men and 22 women), including cardiologists, geriatricians, nurses, and allied health staff. The focus groups generated the following 3 overarching, interrelated themes: (1) the current state of play, understanding the perceived challenges of patient cardiac monitoring in hospitals, (2) priorities in cardiac monitoring, what parameters new technologies should measure, and (3) cardiac monitoring of the future, "the ideal device."
Ferguson, C, Hickman, L, Phillips, J, Newton, P, Inglis, S, Lam, L & Bajorek, B 2017, 'An mHealth intervention to improve nurses' atrial fibrillation and anticoagulation knowledge and practice: the EVICOAG study', International Journal of Stroke, Stroke Society of Australasia, SAGE Publications, Queenstown, New Zealand, pp. 9-9.
Allida, SM, Inglis, SC, Davidson, PM, Hayward, CS, Shehab, S & Newton, PJ 2016, 'A survey of views and opinions of health professionals managing thirst in chronic heart failure', CONTEMPORARY NURSE, ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, pp. 244-252.View/Download from: Publisher's site
Ferguson, C, Inglis, S, Newton, P, Middleton, S, Macdonald, P & Davidson, P 2016, 'Patient centered approaches to anticoagulation decision making with individuals with heart failure and concomitant atrial fibrillation', Joint International Shared-Decision Making and International Society for Evidence Based Healthcare Conference, Sydney.
McDonagh, J, Ferguson, C, Jha, S, Ivynian, S, Crossley, C, Montgomery, E, Hwang, C, Inglis, S, Singh, G, Davidson, P, Macdonald, P & Newton, P 2016, 'Frailty in hospitalized heart failure patients predicts death and rehospitalisation at 6 months', The Journal of frailty & aging, International Conference on Frailty & Sarcopenia Research, Philadelphia, USA.
Disler, RT, Inglis, SC, Newton, PJ, Currow, DC, Macdonald, P, Glanville, AR, Donesky, D, Carrieri-Kohlman, V & Davidson, PM 2015, 'Perspectives Of Online Health Information And Support In Chronic Disease Respiratory Disease: Focus Group Study', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, International Conference of the American-Thoracic-Society (ATS), AMER THORACIC SOC, Denver, CO.
Disler, RT, Inglis, SC, Newton, PJ, Currow, DC, Macdonald, P, Glanville, AR, Donesky, D, Carrieri-Kohlman, V & Davidson, PM 2015, 'Technology Use In Patients Attending A Cardiopulmonary Clinic', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, International Conference of the American-Thoracic-Society (ATS), AMER THORACIC SOC, Denver, CO.
Ivynian, SE, Hwang, C, McDonagh, J, Digiacomo, M, Inglis, SC & Newton, PJ 2015, 'Impact of multiple symptoms on quality of life and event-free survival in chronic heart failure', EUROPEAN HEART JOURNAL, Congress of the European-Society-of-Cardiology (ESC), OXFORD UNIV PRESS, London, ENGLAND, pp. 128-128.
Ferguson, C, Inglis, S, Newton, P, Middleton, S, Macdonald, P & Davidson, P 2015, 'Education & Practice Gaps on Atrial Fibrillation: A Survey of Cardiovascular Nurses', Australasian Cardiovascular Nursing College, Sydney.
Ferguson, C, Inglis, S, Newton, P, Middleton, S, Macdonald, P & Davidson, P 2015, 'Multimorbidity, selfcare & frailty: Important considerations in anticoagulation decision making in heart failure with atrial fibrillation: Outcomes of the AFASTER Study', European Journal of Heart Failure, European Society of Cardiology: Heart Failure, Wiley: 12 months, Seville, Spain.
Inglis, S, Du, H, Newton, PJ, DiGiacomo, M, Omari, A & Davidson, PM 2014, 'PT453 Disease Management Interventions For Improving Self-Management In Lower-Limb Peripheral Arterial Disease: A Cochrane Review.', Global Heart Supplements, Elsevier, Melbourne, Australia, pp. e262-e262.View/Download from: Publisher's site
Peripheral arterial disease (PAD) contributes to psychological burden, poor quality of life and an increased risk of cardiovascular events. Disease management strategies supporting behavioural change and long-term adherence may improve outcomes for people with PAD. However, to our knowledge the evidence relating to self-management interventions for people with PAD has not yet been systematically reviewed or meta-analysed
Ferguson, C, Inglis, S, Newton, P, Middleton, S, Macdonald, P & Davidson, P 2014, 'Frailty and thromboprophylaxis prescription in heart failure and atrial fibrillation: Preliminary findings from the Atrial Fibrillation And Stroke Thromboprophylaxis in hEart failure (AFASTER) cohort study', Global Heart, World Congress of Cardiology, Elsevier, Melbourne, pp. 264-264.
Ferguson, C, Inglis, S, Newton, P, Middleton, S, Macdonald, P & Davidson, P 2014, 'Thromboprophylaxis prescription in hospitalized patients with heart failure and concomitant atrial fibrillation: Preliminary findings from the Atrial Fibrillation And Stroke Thromboprophylaxis in hEart failure (AFASTER) cohort study', Global Heart Journal, World Congress of Cardiology, Melbourne, pp. 109-109.
Ferguson, C, Inglis, S, Newton, PJ, Middleton, S, Macdonald, P & Davidson, PM 2014, 'The Atrial Fibrillation And Stroke Thromboprophylaxis in hEart failuRe (AFASTER) cohort study: 90 day outcomes', European Journal of Heart Failure Supplements, European Society of Cardiology: Heart Failure Congress, Wiley-Blackwell, Athens, Greece, pp. 282-282.
Ferguson, C, Inglis, S, Newton, PJ, Middleton, S, Macdonald, P & Davidson, PM 2014, 'The caregiver role in thromboprophylaxis management in atrial fibrillation', 'Young at Heart' : Australian Cardiovascular Nursing College 8th Annual Scientific Meeting, Gold Coast, Australia.
Inglis, S, Conway, A, Cleland, JG, Horton-Breshears, M & Clark, R 2012, 'Not all reviews are systematic: a meta-review of the quality of current systematic review and meta-analyses for remote monitoring in heart failure.', Heart, Lung and Circulation, Elsevier, Adelaide.
Ferguson, C, Inglis, S, Newton, PJ, Middleton, S, MacDonald, PS & Davidson, PM 2013, 'Stroke prevention in heart failure: time to rethink risk prediction schemes?', World Federation of Neuroscience Nurses Congress, Gifu, Japan.
Ferguson, C, Inglis, S, Newton, PJ, Davidson, PM & Middleton, S 2012, 'Atrial fibrillation and thromboprophylaxis: methods in risk assessment and addressing barriers to adherence: A review.', 'The Aging Heart' - Australian Cardiovascular Nursing College 6th Annual Scientific Meeting, Crowne Plaza, Coogee, Sydney, Australia..
Background: Globally, stroke is one of the worldâs most prevalent, disabling and chronic conditions. Atrial fibrillation is a common arrhythmia in heart failure and presents a significant risk factor for thrombo-embolic, ischaemic stroke. Risk stratification schemata and therapies exist for the treatment of atrial fibrillation and the prophylaxis of stroke, however commonly these therapies are not applied in practice, even when advised in guidelines for numerous reasons. Objective: This presentation aims to identify available validated risk assessment tools for the prediction of stroke risk in patients with atrial fibrillation. Each tool will be evaluated for their benefits and limitations and their consequential implications for clinical practice. Barriers to adherence of available therapies will also be discussed in relation to stroke risk assessment tools and the World Health Organizationâs multidimensional adherence model (2003) Methods: A comprehensive electronic search of the following databases was undertaken: CINAHL, Medline, EBSCO Host, SCOPUS, and the Cochrane Library. Google and Google Scholar search engines were also used. Results: 6 risk prediction assessment tools featured heavily in the search results. Namely; AFI, SPAF, FRS, FGCRS, CHA2DS2 and CHA2DS2-VASc. Each are evaluated and discussed with regards to their advantage and limitations. Conclusions: Whilst valid risk assessment tools are available and their use recommended within practice guidelines their comprehensiveness and holistic patient assessment is questionable. To date, many risk prediction models focus on physical aspects of health and do not assess criteria related to psycho-social aspects of patientâs health and wellbeing such as the patientâs likeliness to adhere to anticoagulation therapy, their ability to take oral medications or assume responsibility for the safe monitoring of their INR. There is much scope for improvement in stroke risk prediction models in atrial fibrill...
Clark, R, Inglis, S, Stewart, S, McAlister, F & Cleland, JG 2011, 'Complex Telemonitoring or a Simple Telephone Call, Which Is More Effective in Post-Discharge Heart Failure (HF) Management?', Journal of Cardiac Failure, Elsevier, Boston, pp. 1-1.
Inglis, S, clark, R, Stewart, S, McAlister, F & Cleland, JG 2011, 'Are Telemonitoring and Structured Telephone Support More Effective in Younger or Older Heart Failure Patients? A Sensitivity Analysis from a Cochrane Review.', Journal of Cardiac Failure, Elsevier, Boston, pp. 1-1.
Karim, K, Lewsey, J & Inglis, S 2011, 'Trends of vascular surgery in Scotland 1991â2007', Journal of Epidemiology and Community Health, BMJ, Edinburgh, pp. 1-2.
Inglis, S 2010, 'A meta-analysis of 8,323 heart failure patients receiving structured telephone support or non-invasive telemonitoring to reduce mortality, hospitalisation and cost', European Journal of Heart Failure Supplements, Wiley, Berlin.
Inglis, S 2010, 'A meta-analysis of 8,323 heart failure patients receiving structured telephone support or non-invasive telemonitoring to reduce mortality, hospitalisation and cost.', European Heart Journal, Oxford Journals, Stockholm.
Inglis, S 2010, 'A seventeen year study of temporal trends in one-year case-fatality following a first hospitalisation for peripheral artery disease in Scotland.', European Heart Journal, Oxford Journals, Stockholm.
Inglis, S 2010, 'Benefits of structured telephone support or telemonitoring in heart failure on mortality, hospitalisation and cost: a meta-analysis of 8,323 heart failure patients.', European Heart Journal, Oxford Journals, Stockholm.
Inglis, S 2010, 'Long-term trends in first hospitalisation for peripheral artery disease in Scotland 1991-2007: a whole population study.', European Heart Journal, Oxford Journals, Stockholm.
Inglis, S 2010, 'Peripheral artery disease as a predictor of outcome in high-risk MI patients: pooled analysis from the high risk MI database initiative (pooled data from CAPRICORN, EPEHESUS, OPTIMAAL and VALIANT).', European Heart Journal, Oxford Journals, Stockholm.
Inglis, S 2010, 'Remote (non-invasive) monitoring in heart failure: effect on length of stay, quality of life, knowledge, adherence and satisfaction in 8,323 heart failure patients: a systematic review.', European Heart Journal, Oxford Journals, Stockholm.
Inglis, S, Lewsey, J, MacIntyre, K & McMurray, JJ 2014, 'Angina or intermittent claudication: which is worse? A comparison of self-assessed general health, mental health and mortality in 7,403 participants in the 2003 Scottish Health Survey.', European Heart Journal, Oxford Journals, Stockholm.
Inglis, S, Lewsey, J, MacIntyre, K & McMurray, JJ 2010, 'Trends in prevalence and 5-year outcomes in subjects reporting angina and intermittent claudication: an analysis of three Scottish population health surveys conducted in 1995, 1998 and 2003', European Heart Journal, Oxford Journals, Stockholm.
Inglis, S 2009, 'Intermittent claudication as a new predictor of outcome in heart failure: Evidence from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA).', European Heart Journal, Oxford, Barcelona.
Inglis, S 2009, 'Peripheral arterial disease is a predictor of worse prognosis at one year in individuals with an incident stroke.', European Heart Journal, Oxford Journals, Barcelona.
Inglis, S 2009, 'Results from a systematic review and meta-analysis of remote (non-invasive) monitoring in 8,323 heart failure patients on length of stay, quality of life, knowledge, compliance and satisfaction', European Journal of Heart Failure Supplements, Wiley, Nice.
Inglis, S 2009, 'Temporal trends in hospitalisation for stroke recurrence following incident hospitalisation for stroke', European Heart Journal, Oxford Journals, Barcelona.
Inglis, S 2008, 'Heart failure in Australia: Seasonal variations in morbidity and mortality in a South Australian heart failure population', Heart Lung and Circulation, Elsevier, Melbourne.
Inglis, S 2008, 'Heart failure in Australia: Seasonal variations in morbidity and mortality in a South Australian heart failure population.', Heart Lung Circulation, Elsevier, Adelaide.
Inglis, S 2008, 'Hot summers and heart failure: seasonal variations in morbidity and mortality in Australian heart failure patients (1994-2005).', European Journal of Heart Failure Supplements, Wiley, Milan.
Inglis, S 2007, 'Is telemonitoring the answer for chronic heart failure patients distal to specialist services?', Heart Lung and Circulation, Elsevier, Christchurch.
Inglis, S 2007, 'Telemonitoring or structured telephone support programs for patients with heart failure: a systematic review and meta-analysis', European Journal of Heart Failure Supplements, Wiley, Hamburg.
Inglis, S 2007, 'The natural history of acute heart failure in chronic heart failure.', European Journal of Heart Failure Supplements, Wiley, Hamburg.
Inglis, S 2006, 'Ten-year follow-up of a nurse-led, multidisciplinary, home-based intervention in typically old and fragile patients: Cost-benefits and outcomes.', Circulation, American Heart Association, Chicago.
Inglis, S 2006, 'Ultimate cost-benefits of altering the natural history of chronic heart failure via a multidisciplinary, home-based intervention: ten year follow-up on typically old and fragile patients.', Heart Lung Circulation, Elsevier, Canberra.
Inglis, S 2004, 'Enantioselective plasma concentration of perhexiline in relation to CYP2D6 phenotype.', Clinical and Experimental Pharmacology and Toxicology, Wiley, Brisbane.
Inglis, S 2004, 'Long-term cost-effectiveness of a nurse-led, home-based intervention in chronic heart failure.', Heart Lung Circulation, Elsevier, Brisbane.
Inglis, S 2003, 'A new solution to an old problem? Effects of a nurse-led home-based intervention in chronic atrial fibrillation.', Heart Lung Circulation, Elsevier, Adelaide.