Alabd, R, Safavi-Naeini, M, Wilson, KJ, Rosenfeld, AB & Franklin, DR 2018, 'A simulation study of BrachyShade, a shadow-based internal source tracking system for HDR prostate brachytherapy.', Physics in medicine and biology, vol. 63, no. 20, pp. 205019-205019.View/Download from: Publisher's site
This paper presents a simulation study of BrachyShade, a proposed internal source-tracking system for real time quality assurance in high dose rate prostate brachytherapy. BrachyShade consists of a set of spherical tungsten occluders located above a pixellated silicon photodetector. The source location is estimated by minimising the mean squared error between a parametric model of the shadow image and acquired images of the shadows projected on the detector plane. A novel algorithm is finally employed to correct the systemic error resulting from Compton scattering in the medium. The worst-case error obtained with BrachyShade for a 13.5 ms image acquisition is less than 1.3 mm in the most distant part of the treatment volume, while for 75% of source locations an error of less than 0.42 mm was achieved.
Wilson, K, Alabd, R, Abolhasan, M, Franklin, D & Safavi-Naeini, M 2019, 'Localisation of the Lines of Response in a Continuous Cylindrical Shell PET Scanner', 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), IEEE Engineering in Medicine and Biology Conference, IEEE, Berlin, Germany.
This work presents a technique for localising the endpoints of the lines of response in a PET scanner based on a continuous cylindrical shell scintillator. The technique is demonstrated by applying it to a simulation of a sensitivity-optimised continuous cylindrical shell PET system using two novel scintillator materials - a transparent ceramic garnet, GLuGAG:Ce, and a LuF$_3$:Ce-polystyrene nanocomposite. Error distributions for the endpoints of the lines of response in the axial, tangential and radial dimension as well as overall endpoint spatial error are calculated for three source positions; the resultant distribution of error in the placement of the lines of response is also estimated.