Bais, B, Lindeboom, R, van Ravesteyn, L, Tulen, J, Hoogendijk, W, Lambregtse-van den Berg, M & Kamperman, A 2019, 'The Impact of Objective and Subjective Sleep Parameters on Depressive Symptoms during Pregnancy in Women with a Mental Disorder: An Explorative Study.', International journal of environmental research and public health, vol. 16, no. 9.View/Download from: UTS OPUS or Publisher's site
Poor sleep quality during pregnancy is associated with both antepartum and postpartum depression and adverse birth outcomes. This study evaluated both objective and subjective sleep quality and the effects on the subsequent course of antepartum depressive symptoms in psychiatric patients. This observational explorative study was embedded in an ongoing study focusing on pregnant women with a mental disorder and was performed in 18 patients (24-29 weeks pregnant). Depressive symptoms were assessed throughout pregnancy using the Edinburgh Postnatal Depression Scale (EPDS) with 5-week intervals. Sleep was assessed with actigraphy, the Pittsburgh Sleep Quality Index (PSQI) and sleep diaries at the start of the study. We studied correlations between sleep parameters and EPDS scores cross-sectionally using Spearman correlation. Next, we studied the course of antepartum EPDS scores over time per sleep parameter using generalized linear mixed modelling analysis. Objectively measured fragmentation index, total PSQI score and 4 PSQI subscales (sleep quality, sleep duration, sleep disturbances and daytime dysfunctions) were significantly correlated with EPDS scores when measured cross-sectionally at the start. Six objectively and subjectively measured sleep parameters had moderate to large effects on the course of depressive symptoms through the third trimester, but these effects were not statistically significant. More research is necessary to explore the causality of the direction between sleep problems and antepartum depressive symptoms we found in psychiatric patients.
Van Ravesteyn, LM, Kamperman, AM, Schneider, TAJ, Raats, ME, Steegers, EAP, Tiemeier, H, Hoogendijk, WJG & Lambregtse-van den Berg, MP 2018, 'Group-based multicomponent treatment to reduce depressive symptoms in women with co-morbid psychiatric and psychosocial problems during pregnancy: A randomized controlled trial.', Journal of affective disorders, vol. 226, pp. 36-44.View/Download from: UTS OPUS or Publisher's site
Depressive symptoms in pregnant women, which are common and debilitating, are often co-morbid with other mental disorders (e.g. anxiety and personality disorders), and related to low socioeconomic status (SES). This situation may hamper treatment outcome, which has often been neglected in previous studies on the treatment of depression during pregnancy. We developed a new group-based multicomponent treatment (GMT) comprising cognitive behavioral therapy, psycho-education and body-oriented therapy and compared the effect on depressive symptoms with individual counseling (treatment as usual, TAU) in a heterogeneous group of pregnant women with co-morbid mental disorders and/or low SES.An outpatient sample from a university hospital of 158 pregnant women who met DSM-IV criteria for mental disorders were included and 99 participants were randomized to GMT or TAU from January 2010 until January 2013. The Edinburgh Depression Scale (EDS) was used at baseline, every 5 weeks during pregnancy and as the primary outcome measure of depressive symptoms at 6 weeks postpartum. Secondary outcome measures included the clinician-reported Hamilton Depression Rating Scale (HDRS), obstetric outcomes and a 'Patient Satisfaction' questionnaire.155 participants were included the intention-to-treat (ITT)-analysis. GMT was not superior above TAU according to estimated EDS (β = 0.13, CI = - 0.46-0.71, p = 0.67) and HDRS scores (β = - 0.39, CI = - 0.82-0.05, p = 0.08) at 6 weeks postpartum. There were no differences in secondary outcomes between the GMT and TAU, nor between the randomized condition and patient-preference condition.The ability to detect an effect of GMT may have been limited by sample size, missing data and the ceiling effect of TAU.GMT is an acceptable treatment for a heterogeneous group of pregnant women with depressive symptoms and co-morbid mental disorders and/or low SES, but not superior to TAU. Further research should focus on understanding and treating co-morbid dis...
van Ravesteyn, LM, Lambregtse-van den Berg, MP, Hoogendijk, WJG & Kamperman, AM 2017, 'Interventions to treat mental disorders during pregnancy: A systematic review and multiple treatment meta-analysis', PLOS ONE, vol. 12, no. 3.View/Download from: Publisher's site
Taylor, CL, van Ravesteyn, LM, van denBerg, MPL, Stewart, RJ & Howard, LM 2016, 'The prevalence and correlates of self-harm in pregnant women with psychotic disorder and bipolar disorder', ARCHIVES OF WOMENS MENTAL HEALTH, vol. 19, no. 5, pp. 909-915.View/Download from: Publisher's site
Kornmann, VNN, Van Ravesteyn, LM, Reif, HM, Sallevelt, PEJM & Krol, RM 2015, 'Unique case of pneumomediastinum due to penetrating injury to the mediastinum', BMJ Case Reports, vol. 2015.View/Download from: Publisher's site
Pneumomediastinum is a rare condition, and mostly occurs following traumatic or iatrogenic tracheal and oesophageal perforation, but spontaneous pneumomediastinum has also been described. We report a case of a 17-year-old woman who presented with a penetrating neck wound after a fall down the stairs. She had an extensive pneumomediastinum without signs of tracheal or oesophageal laceration, rib fractures, pneumothorax or haematothorax. The contaminated wound was surgically explored and extensively lavaged. Prophylactic antibiotic treatment was given and the patient recovered without complications. Direct perforating trauma to the mediastinum is a severe entity, but can be treated by lavage and prophylactic antibiotic therapy.
Van Ravesteyn, LM, Tulen, JHM, Kamperman, AM, Raats, ME, Schneider, AJT, Birnie, E, Steegers, EAP, Hoogendijk, WJG, Tiemeier, HW & Lambregtse-van den Berg, MP 2014, 'Perceived Sleep Quality Is Worse Than Objective Parameters of Sleep in Pregnant Women with a Mental Disorder', JOURNAL OF CLINICAL SLEEP MEDICINE, vol. 10, no. 10, pp. 1137-1141.View/Download from: Publisher's site