Kathleen joined CHERE as a Research Fellow in September 2015. She completed her Masters of Public Health with Monash University. Prior to joining CHERE, Kathleen worked at Covance, a Contract Research Organisation in the Market Access group and has held various roles in the Pharmaceutical industry within Clinical Research. Kathleen has worked on a range of different projects including submissions to the PBAC and PHARMAC on behalf of a Pharmaceutical sponsor, preparation of global value dossiers, monitoring of Phase I to IV trials, and study design and data collection for observational studies and chart audits.
Kathleen is a member of the Economic Evaluation team at CHERE.
Saing, S, Haywood, P, van der Linden, N, Manipis, K, Goodall, S & Meshcheriakova, O 2019, 'Real-World Cost Effectiveness of Mandatory Folic Acid Fortification of Bread-Making Flour in Australia.', Applied health economics and health policy, vol. 17, no. 2, pp. 243-254.View/Download from: Publisher's site
BACKGROUND:In 2009, mandatory folic acid fortification of bread-making flour was introduced in Australia to reduce the birth prevalence of preventable neural tube defects (NTDs) such as spina bifida. Before the introduction of the policy, modelling predicted a reduction of 14-49 NTDs each year. OBJECTIVE:Using real-world data, this study provides the first ex-post evaluation of the cost effectiveness of mandatory folic acid fortification of bread-making flour in Australia. METHODS:We developed a decision tree model to compare different fortification strategies and used registry data to quantify the change in NTD rates due to the policy. We adopted a societal perspective that included costs to industry and government as well as healthcare and broader societal costs. RESULTS:We found 32 fewer NTDs per year in the post-mandatory folic acid fortification period. Mandatory folic acid fortification improved health outcomes and was highly cost effective because of the low intervention cost. The policy demonstrated improved equity in outcomes, particularly in birth prevalence of NTDs in births from teenage and indigenous mothers. CONCLUSIONS:This study calculated the value of mandatory folic acid fortification using real-world registry data and demonstrated that the attained benefit was comparable to the modelled expected benefits. Mandatory folic acid fortification (in addition to policies including advice on supplementation and education) improved equity in certain populations and was effective and highly cost effective for the Australian population.
Saing, S, Haywood, P, Van Der Linden, N, Manipis, K, Meshcheriakova, O & Goodall, S 2019, 'Real world cost-effectiveness of mandatory folic acid fortification of bread making flour in Australia', 11th Health Services and Policy Research Conference, Auckland, New Zealand.
Mulhern, B, Norman, R, Street, D, Lancsar, E, Ratcliffe, J, Shah, K, Devlin, N, Meshcheriakova, O, Saing, S, Manipis, K, Addo, R, Nolasco, V, Brazier, J & Viney, R 2019, 'Valuing EQ-5D-5L: comparing the time trade off and discrete choice experiment valuation methods', 11th Meeting of the International Academy of Health Presference Research, Auckland, New Zealand.
Manipis, K 2019, 'Estimation of the friction period in Australia', 11th Health Services and Policy Conference, Auckland, New Zealand.
Manipis, K, Mulhern, B, Pearce, A, Haywood, P, Viney, R & Goodall, S 2018, 'Estimating the willingness to pay to avoid the impacts of foodborne illnesses: A Discrete Choice Experiment', ISPOR Asia Pacific 2018, Tokyo, Japan.
Manipis, K, Mulhern, B, Haywood, P, Viney, R & Goodall, S 2017, 'Estimating the impact of paid and unpaid sick leave on preferences for avoiding the negative impacts of foodborne illnesses [conference presentation]', 39th Annual Australian Health Economics Society Conference, Sydney.