Transcript - Professor David Currow, Chief Investigator, PaCCSC - Rapid is a quality improvement program incorporating both pharmacovigilance and patient safety principles for a range of medications and non-pharmacological interventions that are frequently prescribed in palliative and supportive care. This international initiative lead by the Australian National Palliative Care Clinical Studies Collaborative aims to evaluate the net clinical benefits and harms of medications and other interventions used in the care of our patients around the world. High quality phase III randomized control trials are expensive and complex particularly when conducted over multiple sites or countries. RAPID is a complimentary way of adding to the evidence base in a prospective manner that is achievable even in resource challenged settings and is genuinely building a community of practice globally. PaCCSC would like to invite you to become involved in this quality improvement program where together with likeminded colleagues from around the world we can help generate new knowledge on a range of medications and non-pharmacological interventions used in everyday palliative and supportive care. Together we can improve the basis of the care we offer, please contact the email address you see on the screen for more information.
The Rapid program is a collaborative, international quality improvement program studying the prospective use of medications and non-pharmacological interventions commonly used in palliative care and cancer symptom management.
The program includes multi-site, consecutive-cohort, post-marketing series that examine interventions to collate data on widespread and longer-term use of medications and non-pharmacological interventions.
The program is called Rapid because it involves:
- Rapid data collection
- Rapid collation and analysis
- Rapid reporting
- Rapid influence on clinical practice
We aim to collect information about interventions commonly used in palliative care and cancer symptom management including:
- the therapeutic benefit of medications and non-pharmacological interventions
- the net clinical response (harms and benefits) of medications and non-pharmacological interventions
- any significant drug/drug, drug/host interactions of medications and non-pharmacological interventions.
We achieve our aims by:
- engaging with palliative care and cancer services around the globe to increase participation in the program
- providing central coordination and support to participating sites through the IMPACCT Trials Coordination Centre
- actively seeking input from participants to nominate new series for investigation.
The Rapid program is successful because it:
- uses minimal resources
- is timely
- involves clinicians from around the globe
- publishes each series to improve the knowledge base for clinical prescribing and use of non-pharmacological therapies
- focuses on interventions that are commonplace in palliative care and cancer practice.
- to evaluate the benefit and toxicity of medications and other interventions being used in palliative care and cancer symptom management
- to describe the indications for medications and other interventions being used in palliative care and cancer symptom management
- to document the frequency of prescribing of common medications and other interventions in this setting.
Who can participate?
Clinicians working with a palliative or cancer population at a location in Australia or overseas
If you participate, you will:
- be collaborating with two investigator initiated clinical trials collaboratives, Palliative Care Clinical Studies Collaborative (PaCCSC) and Cancer Symptom Trials (CST)
- develop the capacity and research capabilities of you and/or your staff who may not otherwise have the opportunity to engage in research
- be contributing to the evidence base to support clinical decision making in palliative care and cancer symptom management
- become a member of PaCCSC or CST, or both - you choose which collaborative/s to join
- receive support and central coordination from the IMPACCT Trials Coordination Centre (ITCC)
Questions? Send your enquiry to Rapid@uts.edu.au
Put your site on the map!
RAPID is truly an international collaboration. Participating sites are indicated on the map below. Find out how to get involved.