Research of the brain
Our mission is to save the brains and minds of a generation of people.
Repair of the brain has previously thought to have been impossible. However; in 2017, a seven-year brain regeneration research project conducted by Professor Vissel achieved breakthrough results. The extraordinary potential for repair of the brain after damage or injury was shown in his laboratory. Scaffolded by the technological focus and multidisciplinary capabilities of UTS, the CNRM is comprehensively driving the next stages of research.
The Centre for Neuroscience & Regenerative Medicine aims to be a world-leader in research and clinical development in brain and memory disorders.
We study and develop new approaches to treatments of disorders of the nervous system that affect memory, movement and mental and emotional health.
Our programs explore disease mechanisms and treatments with emphasis on neural plasticity, regenerative medicine and stem cells. Importantly, the CNRM will develop recent research findings by the Centre that show real potential for brain regeneration after injury or damage.
The research represents a potential critical turning point in medical science. It has the possibility to lead to profoundly new therapeutic approaches for devastating medical conditions currently considered irreversible.
There is an urgent need for effective treatments for disorders of the brain and spinal cord for which there are currently no cures. The CNRM believes a new approach is needed to regenerate and repair brain and spinal cord. We will help deliver it.
Our methodology has three dimensions:
- Deeply understand the mechanisms of normal neural plasticity in learning, movement and mental health
- Think differently about how plasticity mechanisms go wrong in disorders such as Parkinson’s, Alzheimer’s and mental health problems
- Break from mainstream paradigms as required to work towards innovations such as novel therapeutic drugs and regenerative medicine technologies.
Learning, Memory and Movements Program
The Centre will create a platform for comprehensive studies that will drive research in three key areas:
- Normal cognition and learning, and the molecular, cellular, circuit and behavioural levels;
- The relationship between normal learning mechanisms and diseases such as Alzheimer’s disease and Parkinson’s disease; and
- Repositioning research efforts around new insights into Alzheimer’s and Parkinson’s disease towards a new heuristic process
This platform will employ core technologies, tools and resources that researchers can explore, test and integrate into research at the centre.
In the short-term, there are five projects that the Learning, Memory and Movement Program will focus on:
Obtain a deep understanding of potential mechanisms in the brain to drive regeneration and repair as a therapeutic strategy after injury and disease.
- Learning and Memory
Revealing new molecular, cellular and behavioural mechanisms that form the links between Alzheimer’s disease and traumatic disorders such as Post Traumatic Stress Disorder.
- Parkinson’s disease
Develop new theories and understandings with a view to establishing a new clinical program.
- Stroke and Acute Injury
Seek novel insights into the mechanisms of brain damage that occur subsequent to acute stroke – particularly with inflammation.
- Alzheimer’s disease
Re-frame and develop new theories around Alzheimer’s disease with a view to establishing new clinical programs.