New class of tiny sensors become cellular explorers
Researchers from the UTS Institute for Biomedical Materials and Devices (IBMD) have developed a new microscopy technique, aimed at improving the resolution and sensitivity of nanoscale imaging. The discovery allows the human eye to track a single molecule and inspect its behaviour inside a living cell.
The pioneering research, published in the Nature journal Light: Science & Applications, means problems with imaging resolution and sensitivity can be overcome using relatively inexpensive, standard microscopes
Using a new class of nanoparticle sensors - upconversion Super Dots - that convert low-energy near-infrared photons into high-energy visible emissions, scientists have defined how many single photons are needed for the human eye to track a colour-tagged single molecule inside a living cell. The answer is 4000 photons per 100 milliseconds under a simple microscope setup!
Read the full story in the Institute for Biomedical Devices news.