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The Molecular Biosciences Team aim to identify new technologies, therapies and preventative medicines by understanding the basic science which underpins these discoveries. Our multidisciplinary team is formed by the combination of expertise in:
- Acute Spinal Cord and Brain Injury
- Membrane Physiology
- Obesity related Metabolic and Neural Disorders
- Cardiovascular Disease and Regenerative Medicine
- Respiratory Diseases
Dr Hui Chen
Hui’s current research is in the maternal programming on neural and metabolic disorders in the offspring, including maternal obesity and maternal smoking. She is particularly interested in changes of brain glucose metabolism and mitochondrial function during brain injury.
Dr Joshua Chou
Joshua's current research is developing biomaterials for bone fracture regeneration and understanding the cell mechanism and the Wnt signaling pathways of bone remodeling cells in search of identifying key targets for therapeutic intervention in osteoporosis.
Dr Charles Cranfield
Charles’s current research is in the biophysics of antimicrobial peptide-membrane interactions using tethered bilayer lipid membranes (opens an external site). He is also developing improved electrically active implantable electrodes with his industry partner SDx Tethered Membranes Pty Ltd (opens an external site)
Dr Cathy Gorrie
Cathy’s research focuses on neuroprotection and functional recovery following trauma to the central nervous system. She has explored several different strategies for spinal cord injury repair and is also investigating mitochondrial dysfunction following brain injury.
Dr George Herok
George’s current research is studying the effects of brain trauma on mitochondrial function and the contribution of several metabolic markers to post-injury neural survival.
Associate Professor Loraine Holley
Loraine’s research interests encompass the application of physics principles to emerging biomedical technologies and the role of regulatory processes for the safe, effective and timely availability for early entry biomedical technologies.
Dr Kristine McGrath
Kristine’s current research is in the chronic sub-acute inflammatory and oxidative stress mechanisms that underlie the pathogenesis of many chronic diseases, in particular type 2 diabetes and the major cardiovascular disease, atherosclerosis. Her research focuses on genes or compounds that have the potential to influence the inflammation and oxidative stress that underlies these two particular pathologies.
Associate Professor Brian Oliver
Brian leads a team of researchers investigating the pathophysiology of respiratory diseases, with a particular emphasis on understanding basic mechanisms leading to disease initiation, exacerbation and progression.
Dr Pawan Sharma
Pawan’s laboratory is focused on understanding the pathophysiology of chronic lung diseases such as asthma and COPD, and in particular fibrotic mechanisms in human cellular and murine models. His research offers a great opportunity to turn the bench-side science into therapeutics that could make a meaningful impact on the lives of patients.
Associate Professor Stella Valenzuela
Stella has combined her cell and molecular background into leading research in the field of bionanotechnology. Her group is currently investigating the biology of spontaneous membrane inserting proteins, with a particular focus on human CLIC1. This includes understanding the role of these proteins in cell physiology across multiple species including humans, algae and heat stressed plants. Her group are also researching the application of gold nanoparticles as therapeutic agents for regulating immune cells and neuronal cell stimulation. She works on a number of these projects with her industry partner SDx Tethered Membranes Pty Ltd and collaborators based at UTS, UNSW and ANSTO.
Over the past decade, Dr Lele Jiang has dedicated her research in unraveling the biological function of intracellular chloride ion channel protein CLIC1, in particular in inflammation. More recently she has expanded her research to incorporating cutting edge bionanotechnology into investigating modification of CLIC1 interaction with biological membranes in therapeutic potentials.
For more information about the Molecular Biosciences Team please email firstname.lastname@example.org.